Protein Alignment caup and Meis1

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_034919.1
• Gene: Meis1 / 17268
• MGIID: 104717
• Length: 465
• Species: Mus musculus
• Alignment Length: 311
• Identity: 70/311 - (22%)
• Similarity: 115/311 - (36%)
• Gaps: 101/311 - (32%)

  Fly   192 TEMSAWT-----SASLQ-------STTGYYSY------------DPTLAAYGYG----PNYDLAA 228
            |:..:|.     :||.:       |:.|:.|:            |.::|:...|    |:.|...
Mouse   208 TDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKR 272

  Fly   229 RRKNATRESTAT--LKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMT 291
            .:|.......||  ::|||.:|..:|||::.:|..||..|.:|:.||:.||.|||||:.:.
Mouse   273 HKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQP---- 333

  Fly   292 WEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEVDSSGDQKLDLDR 356
                         |:  |:..:....|...:.:....|..::             .|.|.:.: |
Mouse   334 -------------MI--DQSNRAVSQGTPYNPDGQPMGGFVM-------------DGQQHMGI-R 369

  Fly   357 EPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHHQ 421
            .| .|.:|.|  .|....|...:.....||.|:   ...|||.|::|...           .|..
Mouse   370 AP-GLQSMPG--EYVARGGPMGVSMGQPSYTQA---QMPPHPAQLRHGPP-----------MHTY 417

  Fly   422 MDQPYYHP-----GGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVAD 467
            :....:||     ||           |.:|     |:|:.||.|.:.:..|
Mouse   418 IPGHPHHPAVMMHGG-----------QPHP-----GMPMSASSPSVLNTGD 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	17/37 (46%)
		IRO	455..472	CDD:214716	4/13 (31%)
Meis1	NP_034919.1	Meis_PKNOX_N	108..192	CDD:465140
		Homeobox_KN	291..329	CDD:428673	17/37 (46%)
		PABP-1234	<326..457	CDD:130689	38/193 (20%)