DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caup and Tgif2lx2

DIOPT Version :9

Sequence 1:	NP_524046.2	Gene:	caup / 39440	FlyBaseID:	FBgn0015919	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	NP_001136222.1	Gene:	Tgif2lx2 / 100039551	MGIID:	3800824	Length:	231	Species:	Mus musculus

Alignment Length:	199	Identity:	47/199 - (23%)
Similarity:	93/199 - (46%)	Gaps:	27/199 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 ESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTED 300
            :|...|:.||.||:.|.|||..:|.||:..|.::..|||.||.|.|:.|:      ||.:.|...
Mouse    48 KSVKILRDWLCEHQFNAYPTVADKRMLSKNTDLSYLQVSNWFVNIRKHLR------WEIRYKPYS 106

  Fly   301 -DDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQL------IKSELGKAEKEVDSSGDQKL----DL 354
             ..:|..::..:::.:....::.|: |:....:      |:.:..:....::||.:||:    ::
Mouse   107 LSHEGQAANAAQKQHSNPSEEVKTQ-FNENADMQDLPLPIRQDSEEKVPYLESSPNQKVIAEDNI 170

  Fly   355 DREPHNLVAMRGLAPYATPPGAHPMHAA-YSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQ 418
            ::|....:.    .|:::|..|.|.... :||:....:...    |:.:..::|::|..|.|..|
Mouse   171 EKEEKISIT----EPWSSPEVAWPEEKPDFSSFYMLVDVAV----QKAKEMEEQKKQNPNPQGPQ 227

  Fly   419 HHQM 422
            ...|
Mouse   228 QQFM 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	19/38 (50%)
caup	NP_524046.2	IRO	455..472	CDD:214716
Tgif2lx2	NP_001136222.1	Homeobox_KN	56..94	CDD:283551	18/37 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900