Protein Alignment caup and irx1

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_001188351.1
• Gene: irx1 / 100038208
• XenbaseID: XB-GENE-486817
• Length: 467
• Species: Xenopus tropicalis
• Alignment Length: 582
• Identity: 160/582 - (27%)
• Similarity: 234/582 - (40%)
• Gaps: 187/582 - (32%)

  Fly    84 VVGGDVPVGLSSAAQDLPSRGSCCENGRPIITDPVSGQTVCSCQYDPARLAIGGYSRMALPSGGV 148
            |.||:.| |:.:||....:..:...:|||...|                  :|..|..|:.|
 Frog    19 VYGGERP-GVLAAAAAAAAAAAAAGSGRPTGAD------------------LGSSSTAAVTS--- 61

  Fly   149 GVGVYGGPYPSNEQNPYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDP 213
            .:|:|..||.:...:.:.....|.:.| :.:.:.|.:|| :|....:.:.:   .:|.|||.|
 Frog    62 VLGMYASPYSAPNYSAFLPYTTDLTLF-SQMGSQYELKD-NPGVHPATFAA---HTTPGYYPY-- 119

  Fly   214 TLAAYGYGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFA 278
              ..:.||.    ..|.||||||||:||||||:||:|||||||||||||||||||||||||||||
 Frog   120 --GQFQYGD----PGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFA 178

  Fly   279 NARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKE 343
            |||||||||||:||..::|.:|:..|..::.:.||:. |..::..|:.|            .:|.
 Frog   179 NARRRLKKENKVTWGARSKEDDNIFGSDTEGDHEKNE-DDEEIDLESID------------IDKI 230

  Fly   344 VDSSGDQKLDLDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQ 408
            .|:.|:|..:.:.|                                          :::|.:|.:
 Frog   231 DDNDGEQSNEEEDE------------------------------------------KLEHLRQGE 253

  Fly   409 QQ-----------------QQNQQQLQHHQMDQP---YYHPGGYGQEESGEFAAQKNPLSRDCGI 453
            ::                 .::...|.....|..   ...|||.|..:                :
 Frog   254 KESFKKESEVMIPSSDGLKSKDSLSLGKESSDTSNTRIVSPGGQGNIQ----------------V 302

  Fly   454 PVPASKPKIWSVADTAAC------KTPPPTAAYLGQNFYPPSSADQQLPHQP------------- 499
            | |.:||||||:|:||..      .:|||:.|   .:..||......||...
 Frog   303 P-PHNKPKIWSLAETATSPDGALKSSPPPSQA---NHTSPPIQHPAFLPSHGLYTCQIGKFHNWT 363

  Fly   500 ----LQQHQQQQLQQLQQQQQHH--HHPHHHHPHHSMELGSPLSMMSSYAGGSPYSRIPTAYTEA 558
                |.|.....::.|.....||  ||.|||...|..   :||
 Frog   364 NGAFLTQSSLINMRSLLGVNPHHVAHHNHHHLQAHQQ---APL---------------------- 403

  Fly   559 MGMHLPSSSSSSSSTGKLPPTHIHPAPQRVGFPEIQPDTPPQTPPTMKLNSSGGSSSSSGSS 620
            :..:| ||.||..:..:..|.|    ..|...|  :.::|||..|:.:.......|...|:|
 Frog   404 LATNL-SSLSSDKTPERTSPKH----SDRENLP--RTESPPQLKPSFQAVRENTLSQQEGTS 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	35/37 (95%)
		IRO	455..472	CDD:214716	10/22 (45%)
irx1	NP_001188351.1	Homeobox_KN	145..183	CDD:428673	35/37 (95%)
		IRO	303..320	CDD:214716	11/17 (65%)