Protein Alignment caup and irx5

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_001165398.1
• Gene: irx5 / 100038201
• XenbaseID: XB-GENE-484376
• Length: 486
• Species: Xenopus tropicalis
• Alignment Length: 526
• Identity: 160/526 - (30%)
• Similarity: 219/526 - (41%)
• Gaps: 124/526 - (23%)

  Fly   105 SCCENGRPIITDPVS---GQTVCSCQYDPARLAIGGYSRMALPSGGVGVGVYGGPYPSNEQNPYP 166
            ||......:|:.|.:   |::.....:.|    ..|.:.....|.|.             .:|..
 Frog    23 SCPAYSTTVISGPRTDELGRSPSGSAFSP----YAGSTAFTASSAGF-------------NSPLQ 70

  Fly   167 SIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLAAYGYG-PNYDLAARR 230
            ..|...:||.:.:.:||.             .||.:..:.||:.|...|..|.|| |.|     |
 Frog    71 YSGDPAAAFTSYVGSPYD-------------HSAGMAGSLGYHPYAAPLGTYPYGDPAY-----R 117

  Fly   231 KNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPK 295
            |||||::||||||||:||:|||||||||||||||||||||||||||||||||||||||||||.|:
 Frog   118 KNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPR 182

  Fly   296 NKTEDDDDGMMSDDEKEK---------------DAGDGGKLSTEAFDPGNQLIKSELGKAEKEVD 345
            |::||::|....|.||.:               |||| .|.|..|.|  ...::.|: :..||:|
 Frog   183 NRSEDEEDDENIDLEKNEEDDPRKLEEKGDQDGDAGD-QKRSPSAVD--FDRLEGEV-RQGKELD 243

  Fly   346 SSGDQKLDLDREPHNLVAMRGLAPYAT---PPGAHPMHAAYSSYAQSHNTHTHPHP--QQMQHHQ 405
            .:.......:.|..|.:..:..||..:   ||...| .|........|..|.|.|.  ||:.||.
 Frog   244 QTRSDSEQNEVEERNDLLSKNSAPPTSPLCPPDQSP-QAQEDQNLHRHTVHNHHHQSIQQLHHHS 307

  Fly   406 QQQQQQQNQQQLQHHQMDQPYYHPGGYGQEESGEFAAQKNPLSRDC-----GIPVPASKPKIWSV 465
            .|.           |.:|..:.:.           ..|..|::.:.     ..|...||||:||:
 Frog   308 HQS-----------HPLDLVHRNA-----------LVQHGPVTNNATSVIHSPPASTSKPKLWSL 350

  Fly   466 ADTAA----CKTPPPTAAYLG----QNFYPPSSADQQLP----HQPLQQHQQQQLQQLQQQQQHH 518
            |:.|.    .|.....||..|    |:....:|:..:.|    |.|......:.|        ::
 Frog   351 AEIATSSDKVKESSDAAAVAGTTPAQSMVVSASSPSRSPSAQCHFPSNTVLSRPL--------YY 407

  Fly   519 HHP-----------HHHHPHHSMELGSPLSMMSSYAGGSPYSRIPTAYTEAMGMHLPSSSSSSSS 572
            .:|           .|.|.||.....||....:.:..|...:.:..|  ||:.......|.|.:.
 Frog   408 SNPFYPGYTNYGTFSHLHSHHGPSTTSPTVNSTHHFSGINQTVLNRA--EALAKECKLRSQSQAD 470

  Fly   573 TGKLPP 578
            ..|..|
 Frog   471 LNKDTP 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	35/37 (95%)
		IRO	455..472	CDD:214716	8/20 (40%)
irx5	NP_001165398.1	Homeobox_KN	132..170	CDD:428673	35/37 (95%)
		IRO	340..357	CDD:214716	8/16 (50%)