Protein Alignment caup and irx4

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_001263621.1
• Gene: irx4 / 100038068
• XenbaseID: XB-GENE-480570
• Length: 496
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 186/608 - (30%)
• Similarity: 246/608 - (40%)
• Gaps: 200/608 - (32%)

  Fly    94 SSAAQDLPSRGS---CCENGRPIITD---PVSGQTVCSCQYDPARLAIGGYSRMALPSGGVGVGV 152
            ||..|.|.:..|   |||:....::|   ..|.||...|....:||.  ..:|..|.| ...:||
 Frog    11 SSTPQFLMTTNSLSTCCESSGRSLSDSAAAASAQTPVYCPVYESRLL--ATARHELNS-AAALGV 72

  Fly   153 YGGPYPSNE-QNPYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLA 216
            ||.||.|.: ...|.:.|.|.||||:  .|.:..||.:.|..      |.:..|..||.|:.||:
 Frog    73 YGSPYTSTQGYGNYVTYGADASAFYS--LNAFESKDGTGSAH------AGIPQTAAYYPYEHTLS 129

  Fly   217 AYGYG--PNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 279
            .|.|.  ...|.:.||||||||:|:||||||.||:||||||||||||||||||||||||||||||
 Frog   130 QYQYDRYGTMDGSTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 194

  Fly   280 ARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEV 344
            |||||||||||||.|:||..|:.  ...|:|:|::..:..:.:|         ||:|....::||
 Frog   195 ARRRLKKENKMTWPPRNKCSDEK--RPYDEEEEEEEEEDSQKAT---------IKNEKKIVDEEV 248

  Fly   345 DSSGDQKLDL-DREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQ 408
             :..|:.||| |.|..:.:                         :|.::..  ..:|..|||.|.
 Frog   249 -AREDKALDLSDLEDFDAI-------------------------ESESSEC--ELKQPFHHQPQD 285

  Fly   409 QQQQNQQQ-----------------LQHHQMDQP--YYHPGG--------YGQEESGEFAA---Q 443
            ..|..|:.                 ..:.::|:.  .:.||.        .|::..||..|   |
 Frog   286 GHQLRQRDCVNDHCKDVILKMPITPAANQELDRTKICHKPGVDQCEQDVLRGRQRGGESKACFQQ 350

  Fly   444 KNPLSRDCGIPVPASKPKIWSVADTAACKTPPPTAAYLGQNFYPPSSADQQLPHQPLQQHQQQQL 508
            :..|.         |||:|||:|.||..         |.|..||..    .|.||
 Frog   351 QQILD---------SKPRIWSLAHTATS---------LNQTEYPSC----MLKHQ---------- 383

  Fly   509 QQLQQQQQHHHHPHHHHPHHSMELGSPLSMMSSYAGGSPYSRIPTAYTEAMGMHLPSSSSSSSST 573
                                                               |:..||||||||:
 Frog   384 ---------------------------------------------------GLSSPSSSSSSSA- 396

  Fly   574 GKLPPTHIHPAPQRVGFPEIQPDTPPQTPPTMKLNSSGGSSSSSGSSHSSSMHSVTPVTVASMVN 638
                          |..|....|....:|.|...|...|........||:...::|..||:
 Frog   397 --------------VSTPVCVIDRRQDSPVTSLRNWVDGVFHDPLFRHSTLNQALTNTTVS---- 443

  Fly   639 ILYSNT-----DSGYGHGHSHGH 656
              ::.|     ||| ..|.|.|:
 Frog   444 --WATTKGTLIDSG-SLGRSVGN 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	35/37 (95%)
		IRO	455..472	CDD:214716	9/16 (56%)
irx4	NP_001263621.1	Homeobox_KN	160..198	CDD:428673	35/37 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..236		12/34 (35%)
		IRO	356..369	CDD:214716	9/12 (75%)