DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ara and Meis1

DIOPT Version :9

Sequence 1:	NP_524045.2	Gene:	ara / 39439	FlyBaseID:	FBgn0015904	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	XP_006251591.1	Gene:	Meis1 / 686117	RGDID:	1585482	Length:	465	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	69/273 - (25%)
Similarity:	103/273 - (37%)	Gaps:	63/273 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 GPEMGAWTSAGLQPTTGYYSYDPMSAYGGLL---VSNSSYGASYDLAARRKNATRE------STA 268
            ||..|..||         :|.|..|..|..|   |::.|.|...|....:|...:.      :|.
  Rat   230 GPSSGGHTS---------HSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATN 285

  Fly   269 TLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDA 333
            .::|||.:|..:|||::.:|..||..|.:|:.||:.||.|||||:.:.          ..|..:.
  Rat   286 IMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQP----------MIDQSNR 340

  Fly   334 LVSDDEKDKEDLEPSKGSQGSVSLAKDETKEEEDAIDEDQKCLGQANILRAGFGYPSAGSGSGGY 398
            .||.......|.:|..|                 .:.:.|:.:|    :||    |...|..|.|
  Rat   341 AVSQGTPYNPDGQPMGG-----------------FVMDGQQHMG----IRA----PGLQSMPGEY 380

  Fly   399 PGGGGS---SSGHPGGYHPYHHQHPAYYQAG-QQGGMLPFHGENSKLQTDLGDPKNQLGRDCGVP 459
            ...||.   |.|.|.........|||..:.| .....:|.|..:..:....|.|..      |:|
  Rat   381 VARGGPMGVSMGQPSYTQAQMPPHPAQLRHGPPMHTYIPGHPHHPAVMMHGGQPHP------GMP 439

  Fly   460 IPATKPKIWSLAD 472
            :.|:.|.:.:..|
  Rat   440 MSASSPSVLNTGD 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	Homeobox_KN	273..312	CDD:283551	18/38 (47%)
Meis1	XP_006251591.1	Meis_PKNOX_N	108..192	CDD:406806
		Homeobox_KN	290..329	CDD:399131	18/38 (47%)
		PABP-1234	<326..449	CDD:130689	35/163 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810