DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ara and Pknox2

DIOPT Version :9

Sequence 1:	NP_524045.2	Gene:	ara / 39439	FlyBaseID:	FBgn0015904	Length:	717	Species:	Drosophila melanogaster
Sequence 2:	NP_001258207.1	Gene:	Pknox2 / 680549	RGDID:	1590611	Length:	475	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	64/301 - (21%)
Similarity:	108/301 - (35%)	Gaps:	103/301 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 GVYGTPYPSTDQNPYQSIGVDSSAFYSPLSNPYGLKDTGAGPEMG--AWTSAGLQPTTGYYSYDP 235
            |.|....||.:.:....:....::.....:||.|:....:..:.|  |.|:...|..:|...|.|
  Rat   182 GPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQP 246

  Fly   236 MS-------------AYGGLLVSNSSYGASYDLAARRKNATRES-----------TATLKAWLNE 276
            ::             ..|.:.:.|:.  .:.||.:...|..::|           |..:::||.:
  Rat   247 VTMVTSQGQVVTQAIPQGAIQIQNTQ--VNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQ 309

  Fly   277 HKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL---------------KKENKMTWEPKNR 326
            |..:||||:.||..:|..|.:||.||:.||.|||||:               .|:.|....|..|
  Rat   310 HLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQR 374

  Fly   327 -------------------TDDD----------------------------DDALVSDDEKDKED 344
                               |:.|                            ||:|...:|:|::|
  Rat   375 FWPNSIAAGVLQQQGGTPGTNPDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSLDGTEEEDEDD 439

  Fly   345 LEPSKGSQGSVSLAKDETKEEEDAIDEDQKCLGQANILRAG 385
            :|             :|.:|||:..:|:...|...|:...|
  Rat   440 ME-------------EEEEEEEELEEEEADELQTTNVSDLG 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	Homeobox_KN	273..312	CDD:283551	20/38 (53%)
Pknox2	NP_001258207.1	gliding_GltG	5..>77	CDD:411344
		Meis_PKNOX_N	96..181	CDD:406806
		Homeobox_KN	306..345	CDD:399131	20/38 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810