Protein Alignment ara and Irx6

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_071873.2
• Gene: Irx6 / 64379
• MGIID: 1927642
• Length: 439
• Species: Mus musculus
• Alignment Length: 479
• Identity: 155/479 - (32%)
• Similarity: 201/479 - (41%)
• Gaps: 149/479 - (31%)

  Fly   126 AGGGGSCCENG-RP---IMTDPVSGQTVCSCQYDSARLALSSYSRLPAASVGVYGTPYPSTDQNP 186
            |....:|||.. ||   :.:...|..|:|...||| ||..|:...|.|| :|:||.||.:....|
Mouse    20 ASSSATCCETAPRPVSDVASASTSASTLCCTPYDS-RLLGSARPELGAA-LGIYGAPYAAAQSYP 82

  Fly   187 -YQSIGVDSSAFYSPLSNPYGLKDTGAGPEMGAWTSAG----LQPTTGYYSYDPMSAYGGLLVSN 246
             |.:.|.:.......|:..|..|| .||....:.|..|    .:.|.|.|.||   .|||:.:|:
Mouse    83 GYLTYGPEPPTLCGALNPQYEFKD-AAGSFAPSLTQPGAYYPYETTLGQYQYD---RYGGVELSS 143

  Fly   247 SSYGASYDLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARR 311
                     |.||||||||||:.|||||:||:|||||||||||||||||||||||||||||||||
Mouse   144 ---------AGRRKNATRESTSALKAWLHEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARR 199

  Fly   312 RLKKENKMTWEPKN------RTDDDDDAL--VSDDEKDKEDLEPSKGSQGSVSLAKDETKEEEDA 368
            ||||||||||.|||      :.|..:|:|  ::.|.||....:.::|.:.|.....:|.:|||:|
Mouse   200 RLKKENKMTWAPKNKGGEERKADSGEDSLGCLNGDTKDATASQEARGLRLSDLEDLEEEEEEEEA 264

  Fly   369 IDE--------------------------DQKCLGQANILRAGFGYPSAGSGSGGYPGGGGSSSG 407
            .:|                          .::||...   ..|.|.|..........|.....:.
Mouse   265 EEEAAVSAARRLADFQKSTQPLPAPCAAAQERCLESR---ECGLGLPRFSFTEAPQSGEADFITA 326

  Fly   408 HPGGYHPYHHQHPAYYQAGQQGGMLPFHGENSKLQTDLGDPKNQLGRDCGVPIPATKPKIWSLAD 472
            .|||.....|     |.:|.                                    ||:|||||.
Mouse   327 EPGGPTMILH-----YPSGH------------------------------------KPRIWSLAH 350

  Fly   473 TVGC-------KTPPPAY----------------------------------MGH-----QSMPL 491
            |...       .|||.|.                                  .|:     |.:||
Mouse   351 TAAASAVESAPSTPPRAQSPECHMIPRQPSSIRRLLVPRDSEGEEDSPAAKAFGNSTFTLQGLPL 415

  Fly   492 QQQQQQQQQQQQAQHQYPP-SEAG 514
            ......::::.:.:.|||. :|||
Mouse   416 NCAPYPRRREPEVRFQYPSGAEAG 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	60/80 (75%)
		Homeobox_KN	274..312	CDD:428673	35/37 (95%)
Irx6	NP_071873.2	COG5576	<142..232	CDD:227863	68/98 (69%)
		Homeobox_KN	162..200	CDD:428673	35/37 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..270		22/64 (34%)