Protein Alignment ara and meis3

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001006782.1
• Gene: meis3 / 448474
• XenbaseID: XB-GENE-485337
• Length: 453
• Species: Xenopus tropicalis
• Alignment Length: 479
• Identity: 105/479 - (21%)
• Similarity: 148/479 - (30%)
• Gaps: 181/479 - (37%)

  Fly    68 GDASSG-ALSPNALSQNSNAATVVGA-------GGGSSAG--------GGGP-----------AD 105
            |||.:| ||..::|||::...:...|       |.||:.|        .|.|           .:
 Frog    23 GDAHTGRALQHHSLSQSAPYGSTGAAHRVPMPPGMGSNDGLKREKDEIYGHPLFPLLALVFEKCE 87

  Fly   106 LATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDPVSGQTVCSCQYDSARLALSSYSRLPAA 170
            |||....|.:  |:.|       ||..|.:.              |...|.|..|....:..|..
 Frog    88 LATCSPRDNS--GSFP-------GGDVCSSD--------------SFNEDIAVFAKQVRTEKPLF 129

  Fly   171 SVGVYGTPYPSTDQNPYQSIGV------------------------------------------- 192
            |..      |..|....|:|.|
 Frog   130 SSN------PELDSLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIDDRDGSS 188

  Fly   193 -----DSSAFYSPLS--NPYGLKD---TGA------GPEMGAWTSAGLQPTTGYYSYDPMSAYGG 241
                 |.:...:.||  |...::|   ||:      ||     :|.||...:|    |..|..|.
 Frog   189 KSDLEDFTGSCTSLSDQNNSWIRDHDETGSTHSGTPGP-----SSGGLASQSG----DNSSEQGD 244

  Fly   242 LL---VSNSSYGASYDLAARRKNATRE------STATLKAWLNEHKKNPYPTKGEKIMLAIITKM 297
            .:   |::.|.|...||...:|...:.      :|..::|||.:|..:|||::.:|..||..|.:
 Frog   245 CMDNSVASPSTGDDDDLDRDKKRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGL 309

  Fly   298 TLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKEDLEPSKGSQGSVSLAKDET 362
            |:.||:.||.|||||:.:.   ..:..|||                       .||....:.|..
 Frog   310 TILQVNNWFINARRRIVQP---MIDQSNRT-----------------------GQGGAPYSPDGQ 348

  Fly   363 KEEEDAIDEDQKCLGQANILRAGF----------------GYPSAGSGSGGYPGGGGSSSGHPGG 411
            ......:|..|    ...|...||                |:|.||......|...|..  |...
 Frog   349 NMGGYVMDGQQ----HMGIRPPGFQGIPGDYTAAPSTMPMGFPPAGYTPAIPPHSAGLR--HGPS 407

  Fly   412 YHPYHHQHPAYYQAGQQGGMLPFH 435
            .|.|...||.:.......|..|.|
 Frog   408 LHSYLPGHPHHASMILPAGTSPHH 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	30/89 (34%)
		Homeobox_KN	274..312	CDD:428673	17/37 (46%)
meis3	NP_001006782.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..64		8/30 (27%)
		Meis_PKNOX_N	102..186	CDD:465140	14/103 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..272		22/88 (25%)
		Homeobox_KN	286..324	CDD:428673	17/37 (46%)