Protein Alignment ara and irx3

DIOPT Version :9

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001001216.1
• Gene: irx3 / 407888
• XenbaseID: XB-GENE-480486
• Length: 448
• Species: Xenopus tropicalis
• Alignment Length: 478
• Identity: 153/478 - (32%)
• Similarity: 197/478 - (41%)
• Gaps: 141/478 - (29%)

  Fly   161 LSSYSRLPAASVGVYGTPYPSTDQN-------PYQSIGVDSSAFYSPLSNPYGLKDTGAGPEMGA 218
            ||....|......||||||.:....       ||.:    ....:..|.:.|.:||:     .|.
 Frog    31 LSPAGTLSNVLSSVYGTPYAAAAAAQAYGAFLPYSA----ELPIFPQLGSQYEMKDS-----PGV 86

  Fly   219 WTSAGLQPTTGYYSY------DPMSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWLNEH 277
            ..:|...|...:|.|      ||                     :|.||||||||:|||||||||
 Frog    87 QHAAFSHPHAAFYPYGQYQFGDP---------------------SRPKNATRESTSTLKAWLNEH 130

  Fly   278 KKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDK 342
            :|||||||||||||||||||||||||||||||||||||||||||.|::|||::.:|..||.|:||
 Frog   131 RKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSDHEEDK 195

  Fly   343 E------DLEPSKGSQGSVSLAKDETKEEEDAIDEDQKCLGQANILRAGFGYPSAGSGSGGYPGG 401
            .      |||       ::.....|:||:.|..|.|.....:.:
 Frog   196 HEDDEEIDLE-------NIDTEDIESKEDLDDPDTDIHSDSKTD--------------------- 232

  Fly   402 GGSSSGHPGGYHPYHHQHPAYYQA--GQQGGMLPFHGENSKLQTD--LGDP---KNQLGRDCGVP 459
            ..|.|....|:...:.......::  ||:..:.....:...|.:|  ...|   :.:|.|....|
 Frog   233 ARSDSEASDGFEDLNAPEDRLLKSVVGQRQVLNEEPQDKCALSSDAKASQPACEQIKLDRIPSSP 297

  Fly   460 -----IPAT-KPKIWSLADTVGCKTPP---PAYMGHQSMPLQQQQQQQQQQQQAQHQYPPSEAGR 515
                 |||. ||||||||:|......|   |...|          ....|...|||:...|...|
 Frog   298 PLENNIPAAHKPKIWSLAETATTPDNPRRSPNTGG----------SVNTQNLIAQHRLIASPGSR 352

  Fly   516 ----------DQQLFNGAAAPYLR----PHTTAYGGFLGATT-------QQLHTTNN-------- 551
                      .|||....:|.:|:    .||.     ||:.|       :..|:|::
 Frog   353 FQGWTGRAFSAQQLSLLNSAHFLQGLSVSHTA-----LGSGTASFPKAAEPKHSTDSLTDRSSTV 412

  Fly   552 ----SIPYSNMPPQQQQPQQQQQ 570
                .||..|...|..|.:.|.|
 Frog   413 DIEKKIPVLNTAFQPVQRRSQNQ 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	Homeobox_KN	273..312	CDD:283551	37/38 (97%)
irx3	NP_001001216.1	Homeobox_KN	126..165	CDD:310480	37/38 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..250		26/106 (25%)
		IRO	304..321	CDD:214716	11/16 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..410		3/22 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7951
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4061
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351833at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5654
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.100