Protein Alignment ara and irx1a

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_997067.2
• Gene: irx1a / 403019
• ZFINID: ZDB-GENE-040707-1
• Length: 426
• Species: Danio rerio
• Alignment Length: 548
• Identity: 166/548 - (30%)
• Similarity: 225/548 - (41%)
• Gaps: 157/548 - (28%)

  Fly   109 GGSLDGNGVGTTPT--AGGAGGGGSCCENGRPIMTDPVSGQTVCSCQYDSARLALSSYSRLPAAS 171
            ||  |..|| .||:  ||.|..|||.                      .:|..|:||.
Zfish    20 GG--DRPGV-LTPSSRAGSAEIGGSA----------------------SAAAAAVSSV------- 52

  Fly   172 VGVYGTPYPSTDQNPYQSIGVDSSAFYSPLSNPYGLKDT-GAGP-EMGAWTSAGLQPTTGYYSY- 233
            :|:|...:..:...||.|..:   |.:|.:.:.|.|||: |..| ...|.||....| .|.:.|
Zfish    53 LGMYPYAHNYSAFLPYTSADL---ALFSQMGSQYDLKDSPGVHPASFAAHTSPAFYP-YGQFQYG 113

  Fly   234 DPMSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMT 298
            ||                     ||.||||||||:|||||||||:||||||||||||||||||||
Zfish   114 DP---------------------ARPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMT 157

  Fly   299 LTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKE--------DLEPSKGSQGSV 355
            ||||||||||||||||||||:||..  |:.||::...||:|.|.|        |||       |:
Zfish   158 LTQVSTWFANARRRLKKENKVTWGA--RSKDDENIFGSDNEGDAEKNEDEEEIDLE-------SI 213

  Fly   356 SLAKDETKEEEDAIDEDQKCLGQANILRAGFGYPSAGSGSGGYPGGGGSSSGHPGGYHPYHHQHP 420
            .:.|.:..:.:.:.:||:....:...|
Zfish   214 DIDKIDDNDGDQSNEEDEDKRAELESL-------------------------------------- 240

  Fly   421 AYYQAGQQGGMLPFHGENSKLQTDLGDPKNQLGRDCGVPIP-ATKPKIWSLADTVGCKTPPPAYM 484
               |..:.....|..|.|:  .|.:..|    ||..|..:| :.||||||||:|.
Zfish   241 ---QEKRHASKEPSDGNNN--TTRVLSP----GRQGGFQVPVSNKPKIWSLAETA---------- 286

  Fly   485 GHQSMPLQQQQQQQQQQQQAQHQYPPSEAGRDQQLFNGAAAPYLRPHTTAYGGFLGATTQQLHTT 549
               :.|...|:........:...:.||..     |:......:   |....|.|||..:.....:
Zfish   287 ---TSPDSAQKPTSPSVPVSHPAFLPSHG-----LYTCQIGKF---HNWTNGAFLGQNSLLNVRS 340

  Fly   550 NNSIPYSNMPPQQQQPQQQQQQLQQGGTIHTTGSSSGPIIPLQFHNRHPQQQQQLQQQSQSTASQ 614
            ...:...|.|.||||.|.....||    :.:.|::..  :|.....:|..::..|:.:|.:...:
Zfish   341 FLGVNQHNHPAQQQQQQTGPASLQ----VLSAGNTDK--MPEDLSPKHIDRENVLRNESPTQPLK 399

  Fly   615 RAMGFLEAQPDTPPQTPPNMKVLSGALS 642
            .:...|...|..  |.....:||: |||
Zfish   400 SSFRPLHDSPRN--QQESTQRVLT-ALS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	57/80 (71%)
		Homeobox_KN	274..312	CDD:428673	36/37 (97%)
irx1a	NP_997067.2	Homeobox_KN	133..171	CDD:428673	36/37 (97%)
		IRO	<276..289	CDD:214716	9/25 (36%)