Protein Alignment ara and Irx3

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_006255254.1
• Gene: Irx3 / 307721
• RGDID: 1307424
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 160/510 - (31%)
• Similarity: 203/510 - (39%)
• Gaps: 148/510 - (29%)

  Fly    91 GAGGGSSAG-----GGGPADLATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDPVSGQTVC 150
            |.|||||||     |.|.::||..|||                                  ..|.
  Rat    25 GGGGGSSAGGRSGPGAGASELAASGSL----------------------------------SNVL 55

  Fly   151 SCQYDSARLALSSYSRLPAASVGVYGTPYPSTDQNPYQSIGVDSSAFYSPLSNPYGLKDTGAGPE 215
            |..|.:...|.::    .||:...||...|...:.|          .:..|...|.|||: .|.:
  Rat    56 SSVYGAPYAAAAA----AAAAAQGYGAFLPYATELP----------IFPQLGAQYELKDS-PGVQ 105

  Fly   216 MGAWTSAGLQPTTGYYSY------DPMSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWL 274
            ..|..:|...|...:|.|      ||                     :|.||||||||:||||||
  Rat   106 HPATAAAFPHPHPAFYPYGQYQFGDP---------------------SRPKNATRESTSTLKAWL 149

  Fly   275 NEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDE 339
            |||:|||||||||||||||||||||||||||||||||||||||||||.|::|||::.:|..|:.|
  Rat   150 NEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSERE 214

  Fly   340 KDKEDLEPSKGSQ----------------GSVSLAKDETKEEEDAIDEDQKCLGQANILRAGFGY 388
            ::.|:.:..:|.:                |...||.|:..||.|..:.|....| :.:..||..:
  Rat   215 EEDEEEDEEEGKRELEMEEEELAGEEEDTGGEGLADDDEDEEIDLENLDSAAAG-SELTLAGTAH 278

  Fly   389 PSAGSGSGGYPGGGGSSSG--------HPGGYHPYHHQHPAYYQAGQQGGMLPFHGENSKLQTDL 445
            .:...|.|.......|.|.        .|..........|...:|                  ..
  Rat   279 RNGDFGLGPISDCKNSDSDDSSESLEERPLSVLSLAPAPPPVARA------------------PA 325

  Fly   446 GDPKNQLGRDCGVPIPA-----TKPKIWSLADTV----GCKTPPPAYMGHQ-----SMPLQQQQQ 496
            ..|....|.|...|.||     .||||||||:|.    ..:..||...|..     :.|..|...
  Rat   326 SPPSPPSGLDPCAPAPAPSSTLQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPPTLQLSP 390

  Fly   497 QQQQQQQAQHQYPPSEAGR----DQQLFNG-AAAPYLRPHTTAYGGFLGATTQQL 546
            .......|.|:...:..|:    ..:.|.| .|.|  |||..:   .||:..|.|
  Rat   391 AAAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPAGP--RPHPLS---MLGSAPQHL 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	56/80 (70%)
		Homeobox_KN	274..312	CDD:428673	36/37 (97%)
Irx3	XP_006255254.1	Homeobox_KN	149..187	CDD:428673	36/37 (97%)
		IRO	345..362	CDD:214716	9/16 (56%)