Protein Alignment ara and Meis2

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_011237639.1
• Gene: Meis2 / 17536
• MGIID: 108564
• Length: 559
• Species: Mus musculus
• Alignment Length: 474
• Identity: 107/474 - (22%)
• Similarity: 155/474 - (32%)
• Gaps: 175/474 - (36%)

  Fly   131 SCCENGRPIMTDPVSGQTVCSCQYDSARLALSSYSRL-----------PAASVGVYGTPYPSTDQ 184
            ||.:...||  |.|..:...|.:.|...|:.||.:..           .|.|....|||.||:..
Mouse   196 SCLKGKMPI--DLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGG 258

  Fly   185 NPYQSIGVDSS------------AFYSPLSNPYGLKDTGAGPEMGAWTSAGLQPTTGYYSYDPM- 236
            :..|| |.:||            ..:.|:::..|........|...      :...|.:|..|:
Mouse   259 HASQS-GDNSSEQGASETEADHLLLWKPMTDRTGCVSVQMSREDRE------ESREGKHSPQPLE 316

  Fly   237 -------------SAYGGLLVSNS--SYGA------SYDLAARRKNATRESTAT--LKAWLNEHK 278
                         |..||..:.||  |.|.      ..|...::|.......||  ::|||.:|.
Mouse   317 NIIIPCQPPFRGESEAGGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHL 381

  Fly   279 KNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKE 343
            .:|||::.:|..||..|.:|:.||:.||.|||||:.
Mouse   382 THPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIV----------------------------- 417

  Fly   344 DLEPSKGSQGSVSLAKDETKEEEDAIDEDQKCLGQANILRAGFGY-PSAGSGSGGYPGGGGSSSG 407
                                         |..:.|:|  ||||.. ||...|:...|      .|
Mouse   418 -----------------------------QPMIDQSN--RAGFLLDPSVSQGAAYSP------EG 445

  Fly   408 HPGGYHPYHHQHPAYYQAGQQG-GMLPFHGENSKLQTDLGDPKNQLG-RDCGVPIPA-TKPKIWS 469
            .|.|         ::...|||. |:.|     :.||:..||..:|.| ...|:..|: |.|::
Mouse   446 QPMG---------SFVLDGQQHMGIRP-----AGLQSMPGDYVSQGGPMGMGMAQPSYTPPQM-- 494

  Fly   470 LADTVGCKTPPPAYMGHQSMPLQQQQQQQQQQQQAQHQYPPSEAGRDQQLFNGAAAPYLRPHTTA 534
                    ||.|..:.| ..|:              |.|.||.......:.:|  .|...|..|
Mouse   495 --------TPHPTQLRH-GPPM--------------HSYLPSHPHHPAMVMHG--GPPTHPGMT- 533

  Fly   535 YGGFLGATTQQLHTTNNSI 553
                   .:.|..|..||:
Mouse   534 -------MSAQSPTMLNSV 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	32/90 (36%)
		Homeobox_KN	274..312	CDD:428673	17/37 (46%)
Meis2	XP_011237639.1	Meis_PKNOX_N	129..213	CDD:465140	6/18 (33%)
		Homeobox_KN	377..415	CDD:428673	17/37 (46%)