Protein Alignment ara and Irx3

DIOPT Version :9

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001240751.1
• Gene: Irx3 / 16373
• MGIID: 1197522
• Length: 522
• Species: Mus musculus
• Alignment Length: 509
• Identity: 161/509 - (31%)
• Similarity: 208/509 - (40%)
• Gaps: 146/509 - (28%)

  Fly    91 GAGGGSSAG-----GGGPADLATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDPVSGQTVC 150
            |.|||||||     |.|.::||..|||                                  ..|.
Mouse    25 GGGGGSSAGGRSGPGAGASELAASGSL----------------------------------SNVL 55

  Fly   151 SCQYDSARLALSSYSRLPAASVGVYGTPYPSTDQNPYQSIGVDSSAFYSPLSNPYGLKDTGAGPE 215
            |..|.:...|.::    .||:...||...|...:.|          .:..|...|.|||: .|.:
Mouse    56 SSVYGAPYAAAAA----AAAAAQGYGAFLPYATELP----------IFPQLGAQYELKDS-PGVQ 105

  Fly   216 MGAWTSAGLQPTTGYYSY------DPMSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWL 274
            ..|..:|...|...:|.|      ||                     :|.||||||||:||||||
Mouse   106 HPATAAAFPHPHPAFYPYGQYQFGDP---------------------SRPKNATRESTSTLKAWL 149

  Fly   275 NEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVS--D 337
            |||:|||||||||||||||||||||||||||||||||||||||||||.|::|||::.:|..|  :
Mouse   150 NEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSERE 214

  Fly   338 DEKDKEDLEPSK-----------GSQ---GSVSLAKDETKEEEDAIDEDQKCLGQANILRAGFGY 388
            :|.::||.|.||           |.:   |...||.|:..||.|..:.|....| :.:..||..:
Mouse   215 EEDEEEDEEESKRELEMEEEELAGEEEDTGGEGLADDDEDEEIDLENLDSAAAG-SELTLAGAAH 278

  Fly   389 PSAGSGSGGYPGGGGSSSGHPGGYHPYHHQHPAYYQAGQQG---------GMLPFHGENSKLQTD 444
            .:...|.|.......|.|                 ....:|         .:.|.....::....
Mouse   279 RNGDFGLGPISDCKTSDS-----------------DDSSEGLEDRPLSVLSLAPPPPPVARAPAS 326

  Fly   445 LGDPKNQLGRDCGVPIPAT---KPKIWSLADTV----GCKTPPPAYMGHQ-----SMPLQQQQQQ 497
            ...|.:.|......|.|::   ||||||||:|.    ..:..||...|..     :.|..|....
Mouse   327 PPSPPSSLDPCAPAPAPSSALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPPTLQLSPA 391

  Fly   498 QQQQQQAQHQYPPSEAGR----DQQLFNG-AAAPYLRPHTTAYGGFLGATTQQL 546
            ......|.|:...:..|:    ..:.|.| .|.|  |||..:   .||:..|.|
Mouse   392 AAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPAGP--RPHPLS---MLGSAPQHL 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	Homeobox_KN	273..312	CDD:283551	37/38 (97%)
Irx3	NP_001240751.1	Homeobox_KN	148..187	CDD:283551	37/38 (97%)
		IRO	345..362	CDD:214716	9/16 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	0.375	Domainoid score	I8067
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3968
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5654
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	7.040