Protein Alignment ara and Irx1

DIOPT Version :9

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_034703.2
• Gene: Irx1 / 16371
• MGIID: 1197515
• Length: 480
• Species: Mus musculus
• Alignment Length: 629
• Identity: 174/629 - (27%)
• Similarity: 222/629 - (35%)
• Gaps: 257/629 - (40%)

  Fly    66 AGGDASSGALSPNALSQNSNAATVVGAGGGSSAGGGGPADLATGGSLDGNGVGTTPTAGGAGGGG 130
            |.|..:.|...|..|      |....|...:|:|..|.|:|                  |||.|.
Mouse    14 AAGPGAYGGERPGVL------AAAAAAAAAASSGRPGTAEL------------------GAGAGA 54

  Fly   131 SCCENGRPIMTDPVSGQTVCSCQYDSARLALSSYSRLPAASVGVYGTPYPSTDQNPYQSIGVDSS 195
            :                            |::|...:.||:....|.|    :.:.:.....|.|
Mouse    55 A----------------------------AVTSVLGMYAAAGPYAGAP----NYSAFLPYAADLS 87

  Fly   196 AFYSPLSNPYGLKDTGAGPEMGAWTSAGLQPTT-------GYYSYDPMSAYGGLLVSNSSYGASY 253
            .| |.:.:.|.|||           :.|:.|.|       .||.|.... ||.
Mouse    88 LF-SQMGSQYELKD-----------NPGVHPATFAAHTTPAYYPYGQFQ-YGD------------ 127

  Fly   254 DLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 318
              ..|.||||||||:|||||||||:||||||||||||||||||||||||||||||||||||||||
Mouse   128 --PGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 190

  Fly   319 MTWEPKNRTDDDDDALVSDD--------EKDKE-DLEPSKGSQGSVSLAKDETKEEE-DAIDEDQ 373
            :||..::: |.:|.||...|        |.|:| |||         |:..|:..|.: |..:||:
Mouse   191 VTWGARSK-DQEDGALFGSDTEGDPEKAEDDEEIDLE---------SIDIDQIDERDGDQSNEDE 245

  Fly   374 KCLGQANILRAGFGYPSAGSG------------SGGYPGGGGSSSGHPGGYHPYHHQHPAYYQAG 426
            :  .:|...||....|::...            |...|.|.......||.....   .|.....|
Mouse   246 E--DKAEAPRARVAPPASARDQSSPLSAAETLKSQDSPLGLVKEVSEPGSTRLL---SPGAAAVG 305

  Fly   427 QQGGMLPFHGENSKLQTDLGDPKNQLGRDCGVPIPATKPKIWSLADTV-----GCKTPPPAYMGH 486
            .||.                              |.:||||||||:|.     ..|..||....|
Mouse   306 LQGA------------------------------PHSKPKIWSLAETATSPDGAPKASPPPPSSH 340

  Fly   487 QS-------MPLQQQQQQQQQQQQAQHQYPPSEA------GR----------------DQQLFNG 522
            .|       .|||..            .:.||..      |:                :.:.|.|
Mouse   341 ASAHGPPSGSPLQHP------------AFLPSHGLYTCHIGKFSNWTNGAFLAQGSLLNMRSFLG 393

  Fly   523 AAAPYLRPHTTAYGGFLGATTQQLHTTNNSIPYSNMPPQQQQPQQQQQQLQQGGTIHTTGSS--S 585
            .:||:..||.                     |:...||..|.|.|...     |.:|...:|  |
Mouse   394 VSAPHAAPHG---------------------PHLTAPPPPQPPVQVAT-----GVLHGEKASARS 432

  Fly   586 GPIIPLQFHNRHPQQQQQLQQQSQSTASQRAMGFLEAQPDTPPQ 629
            .|.:|                       :|.   |..:||:|||
Mouse   433 SPALP-----------------------ERD---LVTRPDSPPQ 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	Homeobox_KN	273..312	CDD:283551	37/38 (97%)
Irx1	NP_034703.2	Homeobox_KN	145..184	CDD:283551	37/38 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..285		27/106 (25%)
		SDA1	<194..>252	CDD:283052	18/69 (26%)
		IRO	309..326	CDD:214716	10/46 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..354		11/35 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..480		21/102 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	0.375	Domainoid score	I8067
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351833at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5654
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.910