Protein Alignment ara and mirr

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: XP_315118.4
• Gene: mirr / 1275837
• VectorBaseID: AGAMI1_011860
• Length: 575
• Species: Anopheles gambiae
• Alignment Length: 705
• Identity: 232/705 - (32%)
• Similarity: 296/705 - (41%)
• Gaps: 231/705 - (32%)

  Fly     5 TQFGYGGFPSASQLLPPSVQTTEDASANVNVNVNEALVMTNAPAMSPTGGQDCQGSQPSGGAGGD 69
            :.|.:.|.||| |...|:|.:...:.....|    |:.:|..|
Mosquito    24 SHFPFRGSPSA-QSTTPTVPSAPSSPPTAPV----AMAVTTVP---------------------- 61

  Fly    70 ASSGALSPNALSQNSNAATVVGAGGGSSAGGGGPADLATGGSLDGNGVGTTPTAGGAGG--GGSC 132
                   |:|.|.:..:||    .|..::|.||                    |.|:||  ||.|
Mosquito    62 -------PSARSASPCSAT----SGPPTSGPGG--------------------AAGSGGSSGGRC 95

  Fly   133 CENGRPIMTDPVSGQTVCSCQYDSARLALSSYSRLPAASV--------GVYGTPY-PSTDQNPYQ 188
            |:.||||.|||:|||||||||||     |.||.||.:|.:        .:|..|| |.|....:.
Mosquito    96 CDTGRPIFTDPISGQTVCSCQYD-----LISYQRLASAGIAGPGGVPLSMYSAPYSPETMAAYFP 155

  Fly   189 SIGVDSSAFYSPLSNPYGLKDTGAGPEMGAWTSAGLQP---TTGYYSYDPMSAYGGLLVSNSSYG 250
            :||.|.:.||   :||     ..||.::....:||..|   .:.|:.||  :|:|   ...:|||
Mosquito   156 AIGADQAPFY---ANP-----AAAGIDLKENLAAGGAPWPYPSVYHPYD--AAFG---YPFNSYG 207

  Fly   251 ASYDLAARRKNATRESTATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKK 315
            ...: .|||||||||:|:|||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   208 MDLN-GARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKK 271

  Fly   316 ENKMTWEPKNRTDDDDDALVSDDE-----KDKEDLEPSKGSQGSVSLAKDETKEEEDAIDEDQKC 375
            ||||||||:||.:|||..|..||:     ||.:::..||.| |:.|....:.....|.:|
Mosquito   272 ENKMTWEPRNRVEDDDVNLDDDDDDNKSLKDDKEILDSKDS-GTGSSEDGDRPSRLDMLD----- 330

  Fly   376 LGQANILRAGFGYPSAGSGSGGYPGGGGSSS------GHPGGYHPYHHQHPAYYQAGQQGGMLPF 434
                   |.|      ||...|...|.|.:|      |.||     ||.||..:.:.     .|.
Mosquito   331 -------RPG------GSEWNGSRNGSGPNSPDIYDRGVPG-----HHHHPLLHPSN-----FPP 372

  Fly   435 HGENSKLQTDLGDPKNQLGRDCGVPIPATKPKIWSLADTVGCKT-------------PPPAYM-- 484
            |     |:..:..|.:......|...|:|||:||||||....::             |.|..|
Mosquito   373 H-----LRPAISTPPDVNHTPSGSTNPSTKPRIWSLADMASKESKDSDSSSPTAGGYPSPGKMPV 432

  Fly   485 ----GHQSMPLQQQQQQQQQQQQAQHQYPPSEAGRDQQLFNGAAAP------YLRPHTTAYGGFL 539
                |....||              |.:|.......:.|:....||      .|..:...:|..:
Mosquito   433 TPLAGRGLNPL--------------HHHPYMRPDFYRNLYGHHLAPGSPEVSLLESYQRTFGATI 483

  Fly   540 GATTQQLHTTNNSIPYSNMPPQQQQPQQQQQQLQQGGTIHTTGSSSG-PIIPLQF--HNRHPQQQ 601
            ||        :|.:|.|..|                  :.|..|.|| |..||..  .|.|..||
Mosquito   484 GA--------HNGLPVSISP------------------LITKASGSGPPFAPLSLTTANHHLHQQ 522

  Fly   602 QQLQQQSQSTASQRAMGFLEAQPDTPPQTPPNMKVLS-----GALSLLPTATQVP 651
            |                    .|.|.|  ||.....|     |..:|.||:..:|
Mosquito   523 Q--------------------HPHTAP--PPGASPASSTSSNGPENLTPTSVSLP 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	63/80 (79%)
		Homeobox_KN	274..312	CDD:428673	37/37 (100%)
mirr	XP_315118.4	COG5576	<202..>284	CDD:227863	70/82 (85%)
		Homeobox_KN	230..268	CDD:428673	37/37 (100%)