Protein Alignment ara and Tgif2lx2

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001136222.1
• Gene: Tgif2lx2 / 100039551
• MGIID: 3800824
• Length: 231
• Species: Mus musculus
• Alignment Length: 288
• Identity: 58/288 - (20%)
• Similarity: 102/288 - (35%)
• Gaps: 93/288 - (32%)

  Fly   247 SSYGASYDLAARRK-NATRE----------STATLKAWLNEHKKNPYPTKGEKIMLAIITKMTLT 300
            ||:|...:...:.| :.:||          |...|:.||.||:.|.|||..:|.||:..|.::..
Mouse    19 SSFGIRLERTCKMKFHDSRELPRGNMLPLKSVKILRDWLCEHQFNAYPTVADKRMLSKNTDLSYL 83

  Fly   301 QVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKDKEDLEPSKGSQGSVSLAKDETKEE 365
            |||.||.|.|:.|:.|  :.::|.:.:.:...|    :...|:...||:    .|....:|..:.
Mouse    84 QVSNWFVNIRKHLRWE--IRYKPYSLSHEGQAA----NAAQKQHSNPSE----EVKTQFNENADM 138

  Fly   366 ED-----AIDEDQKCLGQANILRAGFGYPSAGSGSGGYPGGGGSSSGHPGGYHPYHHQHPAYYQA 425
            :|     ..|.::|.                                      ||....|
Mouse   139 QDLPLPIRQDSEEKV--------------------------------------PYLESSP----- 160

  Fly   426 GQQGGMLPFHGENSKLQTDLGDPKNQLGRDCGVPIPATKPKIWSLADTVGCKTPPPAYMGHQSMP 490
                        |.|:..:....|.:       .|..|:|  ||..:....:..|.....:..:.
Mouse   161 ------------NQKVIAEDNIEKEE-------KISITEP--WSSPEVAWPEEKPDFSSFYMLVD 204

  Fly   491 LQQQQQQQQQQQQAQHQYPPSEAGRDQQ 518
            :..|:.::.::|:.|:   |:..|..||
Mouse   205 VAVQKAKEMEEQKKQN---PNPQGPQQQ 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	29/81 (36%)
		Homeobox_KN	274..312	CDD:428673	18/37 (49%)
Tgif2lx2	NP_001136222.1	Homeobox_KN	59..94	CDD:428673	16/34 (47%)