Protein Alignment ara and irx1

DIOPT Version :10

• Sequence 1: NP_524045.2
• Gene: ara / 39439
• FlyBaseID: FBgn0015904
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001188351.1
• Gene: irx1 / 100038208
• XenbaseID: XB-GENE-486817
• Length: 467
• Species: Xenopus tropicalis
• Alignment Length: 568
• Identity: 173/568 - (30%)
• Similarity: 221/568 - (38%)
• Gaps: 202/568 - (35%)

  Fly    90 VGAGGGSSAGGGGPADLATGGSLDGNGVGTTPTAGGAGGGGSCCENGRPIMTDPVSGQTVCSCQY 154
            :.||..:..||..|..||...:          .|..|...||    |||...|
 Frog    12 LSAGQAAVYGGERPGVLAAAAA----------AAAAAAAAGS----GRPTGAD------------ 50

  Fly   155 DSARLALSSYSRLPAASV-GVYGTPYPSTDQNPYQSIGVDSSAFYSPLSNPYGLKDTGAGPEMGA 218
                  |.|.|.....|| |:|.:||.:.:.:.:.....|.:.| |.:.:.|.|||
 Frog    51 ------LGSSSTAAVTSVLGMYASPYSAPNYSAFLPYTTDLTLF-SQMGSQYELKD--------- 99

  Fly   219 WTSAGLQPTT-------GYYSYDPMSAYGGLLVSNSSYGASYDLAARRKNATRESTATLKAWLNE 276
              :.|:.|.|       |||.|.... ||.              ..|.||||||||:||||||||
 Frog   100 --NPGVHPATFAAHTTPGYYPYGQFQ-YGD--------------PGRPKNATRESTSTLKAWLNE 147

  Fly   277 HKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNRTDDDDDALVSDDEKD 341
            |:||||||||||||||||||||||||||||||||||||||||:||..  |:.:||:...||.|.|
 Frog   148 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGA--RSKEDDNIFGSDTEGD 210

  Fly   342 KE--------DLEPSKGSQGSVSLAK-DETKEEEDAIDEDQKC--LGQAN----------ILRAG 385
            .|        |||       |:.:.| |:...|:...:||:|.  |.|..          ::.:.
 Frog   211 HEKNEDDEEIDLE-------SIDIDKIDDNDGEQSNEEEDEKLEHLRQGEKESFKKESEVMIPSS 268

  Fly   386 FGYPSAGSGSGGYPGGGGSSSG--HPGGYHPYHHQHPAYYQAGQQGGMLPFHGENSKLQTDLGDP 448
            .|..|..|.|.|......|::.  .|||                ||.:
 Frog   269 DGLKSKDSLSLGKESSDTSNTRIVSPGG----------------QGNI----------------- 300

  Fly   449 KNQLGRDCGVPIPATKPKIWSLADTVGC------KTPPPAYMGHQSMPLQQQQQQQQQQQQAQHQ 507
                    .|| |..||||||||:|...      .:|||:...|.|.|:|..            .
 Frog   301 --------QVP-PHNKPKIWSLAETATSPDGALKSSPPPSQANHTSPPIQHP------------A 344

  Fly   508 YPPS------EAGRDQQLFNGAAAPY-----------LRPHTTAYGGF----------LGAT--- 542
            :.||      :.|:.....|||....           :.||..|:...          |.||
 Frog   345 FLPSHGLYTCQIGKFHNWTNGAFLTQSSLINMRSLLGVNPHHVAHHNHHHLQAHQQAPLLATNLS 409

  Fly   543 ----------TQQLHTTNNSIPYSNMPPQQQ---QPQQQQQQLQQGGT 577
                      |...|:...::|.:..|||.:   |..::....||.||
 Frog   410 SLSSDKTPERTSPKHSDRENLPRTESPPQLKPSFQAVRENTLSQQEGT 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ara	NP_524045.2	COG5576	<237..>318	CDD:227863	58/80 (73%)
		Homeobox_KN	274..312	CDD:428673	36/37 (97%)
irx1	NP_001188351.1	Homeobox_KN	145..183	CDD:428673	36/37 (97%)
		IRO	303..320	CDD:214716	11/17 (65%)