Protein Alignment sowah and Sowahb

DIOPT Version :10

• Sequence 1: NP_001137943.2
• Gene: sowah / 39438
• FlyBaseID: FBgn0036302
• Length: 780
• Species: Drosophila melanogaster
• Sequence 2: NP_780479.1
• Gene: Sowahb / 78088
• MGIID: 1925338
• Length: 760
• Species: Mus musculus
• Alignment Length: 739
• Identity: 143/739 - (19%)
• Similarity: 223/739 - (30%)
• Gaps: 311/739 - (42%)

  Fly     6 ELSVAEIRNYMLANECKVTNHALVKHFKKFLTHPQ----SQNEARKRFKTYVTLLSTIKNE-NNQ 65
            |||...:.:::.....:|.|..|:.|||.||..|.    ...|.|:|||.:|..::.::.: :..
Mouse     4 ELSQEALLDFLCQAGGRVRNAELLSHFKSFLRDPHVSPGQLQERRERFKGFVNSVAAVRQDPDGT 68

  Fly    66 KFLILRKKY-------------------------------------------------------V 75
            |:::|:::|                                                       .
Mouse    69 KYVVLKRRYRDLLGEEGLQRPGPVDGKPRGHRRRDPEPQKPPAGAGTQVDVGGSAQKVAGPDPSP 133

  Fly    76 NECPTDEVVERAVAAA-------------------------SGIPEPSSPGGASLNFDSPMR--- 112
            .:.|.....|...|.|                         :|.|.|...|..::..:.|.|
Mouse   134 EDSPNQRTPEPEAAQARGRCAAVGTRGRCCWECQQNGWGQSTGQPLPEDLGDPAVACEKPERAAP 198

  Fly   113 ----------------------QPPPYKPPPMV------TSPPAV-------------------- 129
                                  ..||..||..|      |||||:
Mouse   199 ARDDLGAPGWLREGEAAEHAPGSVPPVWPPTAVEAAGSPTSPPALPPHPAPSREPLELFTAGSPN 263

  Fly   130 ----SIAKEHQ----------------------------ENYQECVDEFTAAIKRIEPARLERRT 162
                .:.::||                            :|:.:...|....:.....|..|...
Mouse   264 HSTQQLQQQHQRTQEWVARYLQVPEPEIQAPTRAWSVLPDNFLQLPSETAFGVSETSSALPEPAL 328

  Fly   163 SVKS---EDLDQQEK------PEKTSRS--NSIDVIDNKENIPRFSFSSEASSASSTSIEKP--- 213
            |..|   ..||:..:      |....||  ..:.:.|..:.:.:.|..||.||:...  |.|
Mouse   329 SFHSLLPVVLDESSESWPGNAPSTVFRSIRCQLSLQDLNDFVEQESHGSEESSSGPK--ESPGTP 391

  Fly   214 --------------EMAD--------------------------------PTAPAAVGDVAENP- 231
                          |:.|                                ||...::||..:.|
Mouse   392 EEGLQPVLRTSSWGELRDPVEDLFLPPNDSPCLIRRDLGYRGNAPSFRKVPTVAKSLGDHPQEPF 456

  Fly   232 --ISVKEATRKFNR-------MASEEE-------AKIISPPAKKKPEK----------------- 263
              :..:.:.|:.:|       .:|:||       .:...||..:||.|
Mouse   457 PALKFRRSVRRSSRTGRTKSPSSSDEEHPDEDLWKRSRRPPRSRKPSKAGALPSPRVDAVLVQKL 521

  Fly   264 ------------QLIEEKDSPEVTLAH-------------PKAKEWIVSMAKANYQELAKMASEY 303
                        ..|..:|.....:.|             .:..||||.:|..::..:..:..|.
Mouse   522 ADANAVASQPHSSWIPSRDGSAALIPHRPSEHRSPLVPLDTREHEWIVRLASGSWLHVLTLFWED 586

  Fly   304 PELVKLQCPATGYTALHWAAKHGNEDVVK-LIAGTYKA----DVNARTNGGYTPLHLATQFGRDN 363
            |:|...:...||||||||.||||:...:: |::|..||    |||.|::.||||||||...|...
Mouse   587 PQLALHRDFLTGYTALHWIAKHGDLCALQDLVSGAQKAGIALDVNVRSSCGYTPLHLAAIHGHQG 651

  Fly   364 IFELLWNVYKANRDIMDWSGNKPLDYSRQRSSVSASTCSSEYAKYFFGADVGNS-FRTLGFIESS 427
            :.:||.....:..:|.|.||.||..|  ..|:||..|..      ..||..|.. |.....::||
Mouse   652 VIKLLVQRLASRVNIRDCSGKKPWQY--LNSNVSGETWQ------LLGAPRGKPIFPVYSLVQSS 708

  Fly   428 QITGGTLGSALTRGKKRAQNRFAT 451
                    |...:.|.|..:|..|
Mouse   709 --------SPARKVKSREVSRNVT 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sowah	NP_001137943.2	HFD_SF	<126..>169	CDD:480273	11/97 (11%)
		ANKYR	<315..>393	CDD:440430	37/82 (45%)
		ANK repeat	315..346	CDD:293786	18/35 (51%)
		ANK repeat	348..380	CDD:293786	12/31 (39%)
Sowahb	NP_780479.1	CSB_WHD	10..78	CDD:439329	17/67 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..152		4/69 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..268		16/96 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..396		7/27 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	445..512		13/66 (20%)
		ANK 1	597..626		16/28 (57%)
		ANKYR	<598..690	CDD:440430	41/99 (41%)
		ANK repeat	598..634	CDD:293786	18/35 (51%)
		ANK repeat	636..668	CDD:293786	12/31 (39%)
		ANK 2	636..666		11/29 (38%)