DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sowah and sowaha

DIOPT Version :9

Sequence 1:	NP_001137943.2	Gene:	sowah / 39438	FlyBaseID:	FBgn0036302	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	XP_002935307.1	Gene:	sowaha / 733810	XenbaseID:	XB-GENE-986451	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	454	Identity:	112/454 - (24%)
Similarity:	182/454 - (40%)	Gaps:	108/454 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRNYMLANECKVTNHALVKHFKKFLTHPQSQNEA--RKRFKTYVTLLSTIKNENNQKFLILRKKY 74
            :.::||....||.|..|:|.||..:..|..:.:|  |.||||:|..::.:::|...|.::|:|||
Frog     8 VLHFMLEQRGKVRNSDLLKKFKPLVDCPDPEKKAQNRARFKTFVNTVAVVRDEAEGKMVVLKKKY 72

  Fly    75 VNECPTDEVV----ERAVAAASGIPEPSSPGGASLNFDSPMRQPPPYKPPPMVTSPPAVSIAKEH 135
            ::.....|..    :..:.|..|:.:|.|              ...::|....|..||.|..:.|
Frog    73 MHLVTEKEGTSGQEDEPIQAMDGVTQPVS--------------VIQHQPKQSATEEPAPSTQRRH 123

  Fly   136 QENYQECVDEFTAAIKRIEPARLERRTSVKSEDLDQQEK--------PEKTSRSNSIDVIDNKEN 192
            .                   .:|..:.|  ||||.||:|        .|..:.:...||.|.:|.
Frog   124 S-------------------TQLLLQGS--SEDLRQQDKHCTIQSDTGESDASAEMTDVTDPREK 167

  Fly   193 IPRFSFSSEASSASST-------------------------------SIEKPEMADPTAPAAVGD 226
             |....|:|..|.:.:                               :.:||.|.....|...|.
Frog   168 -PSSDESNEIESETESKRETVFAIVARMDNAGPVPVPKSWVDAQPKEAAQKPYMLPLRCPQPTGG 231

  Fly   227 VAENP------------ISVKEATR-------KFNRMASEEEAKIISPPAKKKPEKQLI-EEKDS 271
            ...:|            .:|:|..|       :.:|...:|.| ..||..|:..:.|.: |::..
Frog   232 TENDPEGRSTKETPAVNAAVEEVARPVQSRSPRVSRRQYDETA-TKSPHLKRSSKMQKVSEDQKY 295

  Fly   272 PEVTLAHPKAKEWIVSMAKANYQE-LAKMASEYPELVKLQCPATGYTALHWAAKHGNEDVVKLI- 334
            .:|....|...:|:|:.....:.. |..:.....|||..:...:|:||||||||.||.:::|::
Frog   296 SDVVPLDPSEHKWLVTSTNGRWNHTLYGLLLSDGELVGKRDFISGFTALHWAAKTGNNEMMKILI 360

  Fly   335 ----AGTYKADVNARTNGGYTPLHLATQFGRDNIFELLWNVYKANRDIMDWSGNKPLDYSRQRS 394
                ....|.:||.::.|||||||:|....|.:....|...|.||.::.|.||.||..|.::.|
Frog   361 DSVSKNNMKLNVNVKSFGGYTPLHIAAIHDRTDFITSLVRYYHANVNLRDHSGKKPYQYLKKDS 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowah	NP_001137943.2	Ank_4	289..333	CDD:290365	15/44 (34%)
		ANK	<315..393	CDD:238125	34/82 (41%)
		Ank_4	315..368	CDD:290365	24/57 (42%)
		ANK repeat	315..346	CDD:293786	15/35 (43%)
		ANK repeat	348..380	CDD:293786	13/31 (42%)
sowaha	XP_002935307.1	Ank_2	324..410	CDD:372319	31/85 (36%)
		ANK repeat	339..376	CDD:293786	15/36 (42%)
		ANK repeat	378..410	CDD:293786	13/31 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10870
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1531345at2759
OrthoFinder	1	1.000	-	-		FOG0004238
OrthoInspector	1	1.000	-	-		otm49265
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920