DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sowah and sowahcb

DIOPT Version :9

Sequence 1:	NP_001137943.2	Gene:	sowah / 39438	FlyBaseID:	FBgn0036302	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	XP_009298061.1	Gene:	sowahcb / 563244	ZFINID:	ZDB-GENE-061215-96	Length:	462	Species:	Danio rerio

Alignment Length:	463	Identity:	106/463 - (22%)
Similarity:	166/463 - (35%)	Gaps:	148/463 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LANEC--------------KVTNHALVKHFKKFL-THPQSQNEARKRFKTYVTLLSTIKNENNQK 66
            :|.||              :|.|..|..:|:..: ..|..:.|||:.||.:|..::.:|.||.:|
Zfish    25 MATECSQHAVLRFIEERGGRVKNGDLADYFRAAIPQEPALKQEAREAFKRHVDTVAYVKEENGEK 89

  Fly    67 FLILRKKYVNECPTDEVVERAVAAASGIPEPSSPGGASLNFDSPMRQPPPYKPPPMVTSPPA--- 128
            ::.|||::.. |                  |.|.||...:.|.|              :|.|
Zfish    90 YVCLRKRFWG-C------------------PRSAGGERADTDDP--------------APAARAR 121

  Fly   129 ----------VSIAKEHQENYQECVDEFTAAIKRIEPARLERRTSVKSEDLDQQ--EKPEKTSRS 181
                      ...|:.|....:|.|:..|.|..|   |.:|...|.:|.:...:  |:||:
Zfish   122 TLSSGYGTADAGGAETHPHISEEGVNGGTPAELR---AHMENSDSNRSAEQRPKAAEQPEE---- 179

  Fly   182 NSIDVIDNKENIPRFSFSSEASSASSTSIEKPEMADPTAPAAVG--------DVAENPISVKEAT 238
                                  .|::|..|  |...|.:|..||        |..|:|...:|..
Zfish   180 ----------------------RAAATGGE--ERDGPESPGWVGSSPAEQQRDSGESPGRCRECP 220

  Fly   239 RKFNRMASEEEAKIISPPAKKKPEKQLIEEKDSPEVTLAHPKAKEWIVSMAKANYQELAKMASEY 303
                |..|:.||                     ..||| .|....|::|.:..:::.|..:....
Zfish   221 ----RADSDYEA---------------------AAVTL-EPLEHAWMMSASDGHWESLRPLLDTE 259

  Fly   304 PELVKLQCPATGYTALHWAAKHGNEDVVKLIA-----GTYKADVNARTNGGYTPLHLATQFGRDN 363
            |.||..:...||:|.||||||.|..:::.|:.     .....:||||::.||||||||.......
Zfish   260 PALVARKDFVTGFTCLHWAAKLGKHELIVLLVRFAREHRVSVNVNARSSAGYTPLHLAAIHNHLE 324

  Fly   364 IFELLWNVYKANRDIMDWSGNKPLDYSR---------------QRSSVSASTCSSEYAKYFFGAD 413
            :.:||.....|:.:..|:.|.|...|.:               :.....|.....|..::.....
Zfish   325 VVKLLVGALDADVEARDYYGRKACQYLKSDVAQNILEIAGACAEAEGACAGEAEGEAGRWRLSRV 389

  Fly   414 VGNSFRTL 421
            :.:|||.|
Zfish   390 LQSSFRPL 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowah	NP_001137943.2	Ank_4	289..333	CDD:290365	14/43 (33%)
		ANK	<315..393	CDD:238125	29/97 (30%)
		Ank_4	315..368	CDD:290365	22/57 (39%)
		ANK repeat	315..346	CDD:293786	13/35 (37%)
		ANK repeat	348..380	CDD:293786	11/31 (35%)
sowahcb	XP_009298061.1	PHA03169	13..>214	CDD:223003	54/252 (21%)
		Ank_2	241..341	CDD:289560	31/99 (31%)
		ANK	270..>361	CDD:238125	30/90 (33%)
		ANK repeat	271..307	CDD:293786	13/35 (37%)
		ANK repeat	309..341	CDD:293786	11/31 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	127	1.000	Inparanoid score	I4660
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1531345at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24452
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3353
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.930