DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sowah and pyx

DIOPT Version :9

Sequence 1:	NP_001137943.2	Gene:	sowah / 39438	FlyBaseID:	FBgn0036302	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_612015.1	Gene:	pyx / 38037	FlyBaseID:	FBgn0035113	Length:	956	Species:	Drosophila melanogaster

Alignment Length:	192	Identity:	49/192 - (25%)
Similarity:	81/192 - (42%)	Gaps:	30/192 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 EKDSPEVTLAHPKAKEWIVSMAKANYQELAKMASEYPELVKLQCPATGYTALHWAAKHGNEDVVK 332
            :.::|:|....|     :.:.:.|.:.:..::...:...|:.|......||||.||::...:..:
  Fly   224 DPNTPQVYTETP-----LHTASAAGFAKCVQLLLSHNADVRSQFGEGKVTALHLAAENDYVECAR 283

  Fly   333 LIAGTYKADVNARTNGGYTPLHLATQFGRDNIFELLWNVYKANRDIMDWSGNKPLDYSRQRSSVS 397
            |:. .::|:|:.|.....||||||.........:||.: |.||.:.:...|...|..:..:.|.|
  Fly   284 LLL-EHRAEVDCRNASHQTPLHLACLSQSIGTVDLLIS-YGANVNAVYRDGRTALHAAIVKQSRS 346

  Fly   398 ASTCSSEYAKYFFGADVG---------------NSFRT--LGFIE-SSQITGGTLG--SALT 439
            ...|:   |....||||.               |.|.:  ..||| .:.||..|.|  |||:
  Fly   347 LDCCN---ALLKAGADVNKADNYGYTPLHIAALNEFSSCVYTFIEHGADITARTDGRVSALS 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowah	NP_001137943.2	Ank_4	289..333	CDD:290365	9/43 (21%)
		ANK	<315..393	CDD:238125	23/77 (30%)
		Ank_4	315..368	CDD:290365	16/52 (31%)
		ANK repeat	315..346	CDD:293786	9/30 (30%)
		ANK repeat	348..380	CDD:293786	11/31 (35%)
pyx	NP_612015.1	Ank_4	99..153	CDD:290365
		ANK repeat	102..130	CDD:293786
		ANK	127..252	CDD:238125	4/32 (13%)
		ANK repeat	132..163	CDD:293786
		Ank_2	137..226	CDD:289560	0/1 (0%)
		ANK repeat	166..196	CDD:293786
		ANK	198..319	CDD:238125	23/100 (23%)
		ANK repeat	200..229	CDD:293786	0/4 (0%)
		Ank_2	203..296	CDD:289560	15/77 (19%)
		ANK repeat	231..262	CDD:293786	3/35 (9%)
		ANK	268..387	CDD:238125	33/123 (27%)
		ANK repeat	268..296	CDD:293786	9/28 (32%)
		Ank_2	270..364	CDD:289560	29/98 (30%)
		ANK repeat	298..329	CDD:293786	11/31 (35%)
		ANK repeat	331..364	CDD:293786	10/35 (29%)
		Ank_5	353..404	CDD:290568	14/50 (28%)
		ANK repeat	366..396	CDD:293786	7/29 (24%)
		Ion_trans	556..734	CDD:278921
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2336
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.030