DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sowah and Sowahd

DIOPT Version :9

Sequence 1:	NP_001137943.2	Gene:	sowah / 39438	FlyBaseID:	FBgn0036302	Length:	780	Species:	Drosophila melanogaster
Sequence 2:	NP_776140.1	Gene:	Sowahd / 245381	MGIID:	3045274	Length:	327	Species:	Mus musculus

Alignment Length:	268	Identity:	67/268 - (25%)
Similarity:	108/268 - (40%)	Gaps:	63/268 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 SEEEAKIISPPAKKKPEKQLIEEKDSPEVTLAHPKAKEWIVSMAKANYQELAKMASEYPELVKLQ 310
            |||..:...|.:::.      ..:.|..|.| .|:...||::.|:..::.|.:|....|.|:..:
Mouse    89 SEEHLEPAVPGSRRS------SGQGSSRVCL-EPREHAWILAAAECRFEVLLEMLEAEPSLLMRE 146

  Fly   311 CPATGYTALHWAAKHGNEDVVKLIAGTYKA-----DVNARTNGGYTPLHLATQFGRDNIFELLWN 370
            .|.|||:.|||.||||..:.:.|:....:.     ||:|..:||.||||||...|.|.:.::|..
Mouse   147 DPITGYSVLHWLAKHGRHEELILLHDFARRRGLPFDVSAPGSGGLTPLHLAALQGHDMVIKVLVG 211

  Fly   371 VYKANRDIMDWSGNKPLDYSRQRSSVSASTCSSEYAKYFFGADVGNSFRTLGFIESSQITGGTLG 435
            ...|:....|.|||:|..|.|..:|:                    :.|.|...|..:|
Mouse   212 ALGADPSRRDHSGNRPCHYLRPDASL--------------------NLRELSGAEEWEI------ 250

  Fly   436 SALTRGKKR--AQNRFATISGGSLGGVGGAVSRSQSMTVSRRPK-----------KQPGQPISGI 487
               .|.:||  |.|..:..:         ..:.:.|..:.|.|.           |:..||:...
Mouse   251 ---ERDRKRENANNNSSRTT---------TTTTTTSRWLKRTPSASCIKSTGVHYKEASQPVKEK 303

  Fly   488 FKPATEDG 495
            ...:|::|
Mouse   304 KASSTQEG 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowah	NP_001137943.2	Ank_4	289..333	CDD:290365	16/43 (37%)
		ANK	<315..393	CDD:238125	32/82 (39%)
		Ank_4	315..368	CDD:290365	23/57 (40%)
		ANK repeat	315..346	CDD:293786	13/35 (37%)
		ANK repeat	348..380	CDD:293786	12/31 (39%)
Sowahd	NP_776140.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		ANK 1	112..141		7/29 (24%)
		ANK repeat	119..146	CDD:293786	7/26 (27%)
		Ank_2	121..221	CDD:289560	33/99 (33%)
		ANK 2	147..162		9/14 (64%)
		ANK	150..>230	CDD:238125	31/79 (39%)
		ANK repeat	151..187	CDD:293786	13/35 (37%)
		ANK 3	186..216		11/29 (38%)
		ANK repeat	189..221	CDD:293786	12/31 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..311		12/68 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1531345at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44088
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2336
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.910