DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4069 and Klhdc3

DIOPT Version :9

Sequence 1:NP_648590.1 Gene:CG4069 / 39437 FlyBaseID:FBgn0036301 Length:509 Species:Drosophila melanogaster
Sequence 2:NP_001157201.2 Gene:Klhdc3 / 71765 MGIID:2651568 Length:382 Species:Mus musculus


Alignment Length:318 Identity:73/318 - (22%)
Similarity:116/318 - (36%) Gaps:81/318 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 LYTGTKTT--VYNDLFFYNTKTVEWRQLKSP--SGPTP--RSGHQMVAVASNGGELWMFGGEHAS 148
            |:.|...|  ..|.|:.::..|.:|   .:|  ||..|  |.||....:   |..:::|||.   
Mouse    91 LWGGRNDTEGACNVLYAFDVNTHKW---STPRVSGAVPGARDGHSACVL---GKIMYIFGGY--- 146

  Fly   149 PSQLQFHHYKDLWKFALKSRKWERIAAPNGPSP-RSGHRMTVSKKRLFIFGG-------FHDNNQ 205
             .||......|:.|....:..|..:.....|:. |..|..|:....:::|||       ||.||:
Mouse   147 -EQLADCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFHSATMLGNHMYVFGGRADRFGPFHSNNE 210

  Fly   206 SYHYFNDVHIFSLESYQWLKAEIGGAIVPSPRSGCCIAASPEGKIYVWGGYSRAAMKKEADRGVT 270
            .  |.|.:.:|...:..||.......:....||..  |....|::|::|||: |.:.:.      
Mouse   211 I--YCNRIRVFDTRTEAWLDCPHTPVLPEGRRSHS--AFGYNGELYIFGGYN-ARLNRH------ 264

  Fly   271 HTDMFVLSQDKNAGDADNKYKWAPVKPGGYKPKPRSSVGCTVAANGKAYTFGGVMDVDE------ 329
            ..|::..    |.|    .:.|..::|.|..|.||....|.:..: |...|||.....|      
Mouse   265 FHDLWKF----NPG----SFTWKKIEPKGKGPCPRRRQCCCIVGD-KIVLFGGTSPSPEEGLG
DE 320

  Fly   330 ----DDEDVHGQFGDDLLAFDLTSQT---------------------WRLQEIQTKSS 362
                |..|:|      :|.|..:.:|                     |.|..:.|.|:
Mouse   321 FDLIDHSDLH------ILDFSPSLKTLCKLAVIQYSLDQSCLPHDIRWELNAMTTNSN 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4069NP_648590.1 KELCH repeat 69..120 CDD:276965 8/33 (24%)
Kelch_3 80..132 CDD:290151 14/47 (30%)
KELCH repeat 124..179 CDD:276965 12/54 (22%)
Kelch_3 136..189 CDD:290151 12/53 (23%)
Kelch_3 191..244 CDD:290151 14/59 (24%)
Kelch_2 237..297 CDD:284956 13/59 (22%)
KELCH repeat 305..353 CDD:276965 13/78 (17%)
Kelch_5 423..463 CDD:290565
KELCH repeat 426..470 CDD:276965
Klhdc3NP_001157201.2 KELCH repeat 180..236 CDD:276965 15/57 (26%)
Kelch 4 191..249 15/61 (25%)
KELCH repeat 239..283 CDD:276965 13/60 (22%)
Kelch 5 251..301 15/64 (23%)
KELCH repeat 14..62 CDD:276965
Kelch_6 14..61 CDD:372847
Kelch 1 25..77
PLN02153 74..>318 CDD:177814 63/256 (25%)
KELCH repeat 77..124 CDD:276965 10/35 (29%)
Kelch 2 88..138 14/52 (27%)
KELCH repeat 128..173 CDD:276965 12/51 (24%)
Kelch 3 139..189 12/53 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1494
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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