Protein Alignment CG4069 and klhdc4

DIOPT Version :9

• Sequence 1: NP_648590.1
• Gene: CG4069 / 39437
• FlyBaseID: FBgn0036301
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_002936149.3
• Gene: klhdc4 / 394683
• XenbaseID: XB-GENE-987963
• Length: 579
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 224/538 - (41%)
• Similarity: 316/538 - (58%)
• Gaps: 43/538 - (7%)

  Fly     1 MGKKDKNKKKGKGAEKTAMKTDKKQAARQKKMLEKLGEANIADIIQLLEAKEGKIEAISESVCPP 65
            ||||.|.:||.|||||||.|.:||.:.|.||..|.| ||.||: .|.|:||:.:   |.|:.|||
 Frog     1 MGKKGKKEKKVKGAEKTAAKMEKKVSKRSKKDEEDL-EALIAE-FQTLDAKKTQ---IIETSCPP 60

  Fly    66 PTPRSNFTLVCHPEKEELIMFGGELYTGTKTTVYNDLFFYNTKTVEWRQLKSPSGPTPRSGHQMV 130
            |:||.|.:|..||||:|||:||||.:.|.||.:||:|:.||.|...|.::..|:.|..|..||..
 Frog    61 PSPRLNGSLTPHPEKDELILFGGEYFNGQKTFLYNELYIYNIKKNTWSKIDIPNPPPRRCAHQAA 125

  Fly   131 AVASNGGELWMFGGEHASPSQLQFHHYKDLWKFALKSRKWERIAAPNGPSPRSGHRMTVSKKRLF 195
            ||...||::|:||||.|||...||:||||||...|:::.||:|.|..|||.|||||||..|::|.
 Frog   126 AVPQGGGQIWIFGGEFASPDGEQFYHYKDLWVLHLQTKTWEQIKASGGPSGRSGHRMTYCKRQLI 190

  Fly   196 IFGGFHDNNQSYHYFNDVHIFSLESYQWLKAEIGGAIVPSPRSGCCIAASPEGKIYVWGGYSRAA 260
            :|||||::.:.|.|:|||:.|:|:|:.|.|....|. .|.|||||.:..:.:|.:.::||||:..
 Frog   191 VFGGFHESTRDYIYYNDVYTFNLDSFTWAKLSPSGT-APLPRSGCQMTTNQDGSVVIYGGYSKQK 254

  Fly   261 MKKEADRGVTHTDMFVLSQDKNAGDADNKYKWAPVKPGGYKPKPRSSVGCTVAANGKAYTFGGVM 325
            :||:.|:|..|||||:|.|:    .|| |:.|:.:.|.|.||.||:....|:..|.:...||||.
 Frog   255 VKKDVDKGTVHTDMFLLKQE----GAD-KWVWSRLNPSGVKPTPRTGFSGTLGPNNRILLFGGVY 314

  Fly   326 DVDEDDEDVHGQFGDDLLAFDLTSQTWRLQEI----------QTKSSSAEKKDSEESKDVEMSAV 380
            | :|::|.:.|.|.:|:..:|:....|...:|          :..:..||.:.:.||.:|.....
 Frog   315 D-EEEEESIEGDFFNDIYMYDMGKNRWFTGQIKGPKTEKKKRRRGNKQAEAESNSESGEVGAQKP 378

  Fly   381 DKPV-----TTTTDG-IFTV--TVGGPSTSTT---PFVSKIPSLFAKPKPTNVPSPRMNPGMCVC 434
            .:||     ....|| :.|:  .:.|.:||.:   ..|.:.....|: .|...|.||.|..:...
 Frog   379 PEPVEVIKEIVAEDGTVMTIKQVISGSATSESEEEDSVEEEDDEGAR-SPAVEPCPRSNTMIAAK 442

  Fly   435 KGTLYIFGGIFEEDDKQLTYNDFYALDLHKL-EWKVLIPNSLKGHEW-EDSDSSSSDEECSGS-- 495
            :|.||.:||:||..|:|.|.||.|:|||||: |||||:....|..|| ::|||...:|:..|:
 Frog   443 QGVLYAYGGMFEVGDRQFTLNDLYSLDLHKMEEWKVLVEMDPKTQEWLDESDSEDEEEDAEGAEG 507

  Fly   496 -----EEDISSSSSDMDT 508
                 |||..|..||.|:
 Frog   508 GDEEEEEDEDSEDSDEDS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4069	NP_648590.1	KELCH repeat	69..120	CDD:276965	25/50 (50%)
		Kelch_3	80..132	CDD:290151	23/51 (45%)
		KELCH repeat	124..179	CDD:276965	28/54 (52%)
		Kelch_3	136..189	CDD:290151	32/52 (62%)
		Kelch_3	191..244	CDD:290151	24/52 (46%)
		Kelch_2	237..297	CDD:284956	24/59 (41%)
		KELCH repeat	305..353	CDD:276965	14/47 (30%)
		Kelch_5	423..463	CDD:290565	19/39 (49%)
		KELCH repeat	426..470	CDD:276965	23/44 (52%)
klhdc4	XP_002936149.3	PLN02193	<70..>251	CDD:177844	88/181 (49%)
		KELCH repeat	119..174	CDD:276965	28/54 (52%)
		KELCH repeat	177..226	CDD:276965	24/48 (50%)
		KELCH repeat	231..291	CDD:276965	26/64 (41%)
		Kelch_4	293..340	CDD:404322	15/47 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69234
Inparanoid	1	1.050	379	1.000	Inparanoid score	I2026
OMA	1	1.010	-	-		QHG56581
OrthoDB	1	1.010	-	-		D359532at33208
OrthoFinder	1	1.000	-	-		FOG0006519
OrthoInspector	1	1.000	-	-		oto103724
Panther	1	1.100	-	-	LDO	PTHR46063
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5490
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080