Protein Alignment CG4069 and Klhdc4

DIOPT Version :10

• Sequence 1: NP_648590.1
• Gene: CG4069 / 39437
• FlyBaseID: FBgn0036301
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001414476.1
• Gene: Klhdc4 / 307917
• RGDID: 1561676
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 222/532 - (41%)
• Similarity: 306/532 - (57%)
• Gaps: 42/532 - (7%)

  Fly     1 MGKKDKNKKKGKGAEKTAMKTDKKQAARQKKMLEKLGEANIADIIQLLEAKEGKIEAISESVCPP 65
            ||||.|.:|||:||||||.|.:||.:.|.:|..|.| ||.||. .|.|:||:.:   ::|:.|||
  Rat     1 MGKKGKKEKKGRGAEKTAAKMEKKVSKRSRKEEEDL-EALIAH-FQTLDAKKTQ---VTETPCPP 60

  Fly    66 PTPRSNFTLVCHPEKEELIMFGGELYTGTKTTVYNDLFFYNTKTVEWRQLKSPSGPTPRSGHQMV 130
            |:||.|.:|..||||:|||:||||.:.|.||.:||:|:.|:.:...|.::..|..|..|..||.|
  Rat    61 PSPRLNASLSAHPEKDELILFGGEYFNGQKTFMYNELYIYSIRKGTWTKVDIPGPPPRRCAHQAV 125

  Fly   131 AVASNGGELWMFGGEHASPSQLQFHHYKDLWKFALKSRKWERIAAPNGPSPRSGHRMTVSKKRLF 195
            .|...||:||:||||.|||...||:||||||...|.::.||:|.:..|||.||||||...|::|.
  Rat   126 VVPQGGGQLWIFGGEFASPDGEQFYHYKDLWVLHLATKTWEQIRSTGGPSGRSGHRMVAWKRQLI 190

  Fly   196 IFGGFHDNNQSYHYFNDVHIFSLESYQWLKAEIGGAIVPSPRSGCCIAASPEGKIYVWGGYSRAA 260
            :|||||::.:.|.|::||:.|||:::.|.|....|. .|:|||||.:|.:|:|.|.::||||:..
  Rat   191 LFGGFHESTRDYIYYSDVYTFSLDTFLWSKLSPSGP-GPTPRSGCLMAVTPQGSIAIYGGYSKQR 254

  Fly   261 MKKEADRGVTHTDMFVLSQDKNAGDADNKYKWAPVKPGGYKPKPRSSVGCTVAANGKAYTFGGVM 325
            :||:.|:|..|:|||:|..:....|   |:.|..|.|.|.||..||.....||.|.:...||||.
  Rat   255 VKKDVDKGTQHSDMFLLKPEDGGED---KWTWTRVNPSGVKPTVRSGFSVAVAPNHQILVFGGVC 316

  Fly   326 DVDEDDEDVHGQFGDDLLAFDLTSQTWRLQEIQTKSSSAEKK--------DSEESKDVEMSAVDK 382
            | :|::|.:.|.|.:||..:|.....|  ...|.|...:|||        |.|.:.:.|......
  Rat   317 D-EEEEEHLEGSFFNDLYIYDAAKSRW--FAAQLKGPKSEKKRRRRGKADDPEGATEEETGGTSA 378

  Fly   383 P-------VTTTTDG-IFTV----TVGGPSTSTTPFVSKIPSLFAKPKPT-NVPSPRMNPGMCVC 434
            |       ...:.|| :.|:    |..|......|   |.....::...| ..|.||.:..:.|.
  Rat   379 PEPLEVIKEVVSEDGTVITIKQVLTPSGLGVQPPP---KADDSASEASSTGQEPCPRSSAMLAVK 440

  Fly   435 KGTLYIFGGIFEEDDKQLTYNDFYALDLHKL-EWKVLIPNSLKGHEW-EDSDS---SSSDEE-CS 493
            .|.||::||:||..|:|:|.:|.|.|||||: |||.|:....|..|| |:|||   |||||| ..
  Rat   441 HGLLYVYGGMFEAGDRQVTLSDLYCLDLHKMEEWKTLVEMDPKSQEWLEESDSEEDSSSDEEGAE 505

  Fly   494 GSEEDISSSSSD 505
            |.:||....||:
  Rat   506 GGDEDQEEDSSE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4069	NP_648590.1	NanM	64..353	CDD:442289	130/288 (45%)
		KELCH repeat	69..120	CDD:276965	23/50 (46%)
		KELCH repeat	124..179	CDD:276965	28/54 (52%)
		KELCH repeat	305..353	CDD:276965	17/47 (36%)
		Kelch_5	423..463	CDD:433528	18/39 (46%)
		KELCH repeat	426..470	CDD:276965	22/44 (50%)
Klhdc4	NP_001414476.1	None