Protein Alignment CG4069 and Hcf

DIOPT Version :10

• Sequence 1: NP_648590.1
• Gene: CG4069 / 39437
• FlyBaseID: FBgn0036301
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_061507156.1
• Gene: Hcf / 1278452
• VectorBaseID: AGAMI1_010556
• Length: 1952
• Species: Anopheles gambiae
• Alignment Length: 449
• Identity: 102/449 - (22%)
• Similarity: 171/449 - (38%)
• Gaps: 107/449 - (23%)

  Fly    42 ADIIQLLEAKEGKI---EAISESVCPPPTPRSNFTLVCHPEKEELIMFGGELYTGTKTTVYNDLF 103
            ::::....||...|   :.::....|.|.||.....|  ..||.:::|||    |.:..| ::|.
Mosquito    10 SELVPASSAKHNAILRWKRVTNPSGPQPRPRHGHRSV--NIKELMVVFGG----GNEGIV-DELH 67

  Fly   104 FYNTKTVEWRQLKSPSGPTPRSGHQMVAVASNGGELWMFGGEHASPSQLQFHHY-KDLWKFALKS 167
            .|||.|.:| .:.:..|..| .|........:|..:.:|||      .:::..| .:|::  |::
Mosquito    68 VYNTATNQW-YVPATKGDVP-PGCAAYGFVVDGTRILVFGG------MVEYGKYSNELYE--LQA 122

  Fly   168 RKWE----RIAAP-NGPSP--RSGHRMTVSKKRLFIFGGFHD-----NNQSYHYFNDVHIFSLES 220
            .|||    |...| :||.|  |.||..|:...::::|||..:     .|....|.||::|..:::
Mosquito   123 TKWEWKKLRPKPPESGPPPCRRLGHSFTLVGDKIYLFGGLANESDDPKNNIPKYLNDLYILEIKN 187

  Fly   221 --YQW-LKAEIGGAIVPSPRSGCCIAASPEGK-----IYVWGGYSRAAMKKEADRGVTHTDMFVL 277
              .|| :....|.:  |.||......:..:.|     :.::||.|          |....|:::|
Mosquito   188 NQLQWEIPTTFGES--PPPRESHTAVSWYDKKQKKFWLVIYGGMS----------GCRLGDLWLL 240

  Fly   278 SQDKNAGDADNKYKWAPVKPGGYKPKPRSSVGCTVAANGKAYTFGG-----VMDVDEDDEDVHGQ 337
            ..|        ...|...:..|..|.|||....|:..| :.|.|||     :.||..:..:...:
Mosquito   241 DTD--------TMSWTRPRTSGPLPLPRSLHSSTLIGN-RMYVFGGWVPLVLDDVKVEKHEKEWK 296

  Fly   338 FGDDLLAFDLTSQTWRLQEIQTKSSSAEK-------------------KDSEES----------K 373
            ..:.|...:|.:.||...::.|...:..:                   :|....          |
Mosquito   297 CTNTLACLNLETMTWEELDLDTDEENMPRARAGHCAVGIHTRLYIWSGRDGYRKAWNNQVRVCCK 361

  Fly   374 DVEMSAVDKPVT--------TTTDGIFTVTVGGPSTSTTPF-VSKIPSLFAKPKPTNVP 423
            |:....|::|.|        .:|..:.......||.|.... |.|||.  |.|.|...|
Mosquito   362 DLWYLEVERPATASRVQLVRASTHSLEVCWQAVPSASYYILEVQKIPQ--APPPPPPAP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4069	NP_648590.1	NanM	64..353	CDD:442289	79/314 (25%)
		KELCH repeat	69..120	CDD:276965	15/50 (30%)
		KELCH repeat	124..179	CDD:276965	13/60 (22%)
		KELCH repeat	305..353	CDD:276965	13/52 (25%)
		Kelch_5	423..463	CDD:433528	1/1 (100%)
		KELCH repeat	426..470	CDD:276965
Hcf	XP_061507156.1	None