Protein Alignment Pmm2 and SEC53

DIOPT Version :10

• Sequence 1: NP_648589.1
• Gene: Pmm2 / 39436
• FlyBaseID: FBgn0036300
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_116609.1
• Gene: SEC53 / 850499
• SGDID: S000001849
• Length: 254
• Species: Saccharomyces cerevisiae
• Alignment Length: 248
• Identity: 142/248 - (57%)
• Similarity: 177/248 - (71%)
• Gaps: 3/248 - (1%)

  Fly     7 KRDEILLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLNGRKILNEFD 71
            ::.|.|:|||||||||..|..|:.|..:.. ::::.:..||.||||||.|..||| |..:|:|||
Yeast    10 EKPETLVLFDVDGTLTPARLTVSEEVRKTL-AKLRNKCCIGFVGGSDLSKQLEQL-GPNVLDEFD 72

  Fly    72 FIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNGMMNVC 136
            :.|.||||.....|||:..|:.|..||||...:...|:||||||:|:|.:||||:||||||:||.
Yeast    73 YSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVS 137

  Fly   137 PIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPHGWDKTYCLRH 201
            ||||..:.||||.|..||.||::|.|.::.||:||.|..||:||||||||||||.||||||||:|
Yeast   138 PIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQH 202

  Fly   202 IEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEILEL 254
            :|.. .|||||||||||..|||||||:.|.|||.|.|.:|.||.:||||:..|
Yeast   203 VEKD-GFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pmm2	NP_648589.1	HAD_PMM	12..251	CDD:319784	139/238 (58%)
SEC53	NP_116609.1	OtsB	12..>46	CDD:441481	14/34 (41%)
		PMM	35..254	CDD:397425	127/221 (57%)