DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsf2 and srprb

DIOPT Version :9

Sequence 1:	NP_524044.1	Gene:	Tsf2 / 39435	FlyBaseID:	FBgn0036299	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001002572.1	Gene:	srprb / 436845	ZFINID:	ZDB-GENE-040718-311	Length:	266	Species:	Danio rerio

Alignment Length:	195	Identity:	45/195 - (23%)
Similarity:	77/195 - (39%)	Gaps:	44/195 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 RNQQDGTNTSILYEKFRIFESKRYGKPNLL---------------FQDSSRALTVIPEDDQSFTK 430
            |.|...|.:|..|:.    :|:|.....|:               ::|.:||: |...|...|.|
Zfish    87 RTQTSITESSATYKS----KSERGNSWTLIDVPGHESLRTQIVEKYKDVARAI-VFVVDSSIFQK 146

  Fly   431 YLGPAINFIYGIRECPV---PAMTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQ 492
            .:.....|:|.|....:   .|.||.|.. |:.|  |.|..:.|       ||.:::...:|.::
Zfish   147 DVRDVAEFLYSILTDSILAKNAPTLVVAC-NKQD--ITMAKSAK-------LIQQQLEKELNTLR 201

  Fly   493 FIEAGKADISVFD---AGDVYTG--GLNYDLVPFMSEVYNLGEPEYYVVAVAKEDDPDTELTYLK 552
            ...:  |.:|..|   .|.||.|  |.:::    .|::.|..|........:|.:|.|.::..|:
Zfish   202 LTRS--AALSSQDGAVGGSVYLGKKGKDFE----FSQLANRVEFIECKARGSKTEDGDADIDALE 260

Fly 553 552
Zfish 261 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsf2	NP_524044.1	PBP2_transferrin	32..372	CDD:270247
		PBP2_transferrin	450..792	CDD:270247	26/108 (24%)
		TR_FER	452..790	CDD:214514	25/106 (24%)
srprb	NP_001002572.1	SRPRB	58..237	CDD:255367	40/170 (24%)
srprb	NP_001002572.1	SR_beta	61..266	CDD:206691	45/195 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583235
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930