Protein Alignment Tsf2 and Inhca

DIOPT Version :10

• Sequence 1: NP_524044.1
• Gene: Tsf2 / 39435
• FlyBaseID: FBgn0036299
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_038937483.1
• Gene: Inhca / 315963
• RGDID: 1310507
• Length: 715
• Species: Rattus norvegicus
• Alignment Length: 822
• Identity: 249/822 - (30%)
• Similarity: 348/822 - (42%)
• Gaps: 190/822 - (23%)

  Fly     8 VALVGA-----LCFTLANAQHHYDEHKTTRMVWCTKSQAEQYKCQNLTVAIERD--RALFDEVFL 65
            |:|.|:     ||..:        ..||.|  ||..|..|..||.:.     ||  :.:......
  Rat    20 VSLPGSHIRNRLCLAV--------PEKTIR--WCIVSDHEATKCSSF-----RDNMKKVLPAGGP 69

  Fly    66 NLTCFMAYSADECIHHIDREKAHITTLDAGDVFTAG-RYNSLIPIMQEKLEGGFAD-----YQSV 124
            .:.|....|..|||..|...|....|:|...|..|. .::||.|||.|..  |..|     |..|
  Rat    70 AVACVRKTSHLECIRDISANKIDAVTVDGALVAEADLPHHSLKPIMAEYY--GSKDDPQTHYYVV 132

  Fly   125 AVIKKGSLPDLNNLRDMRNKRVCFPWVGSLAGWIVPIHTLQREGGMEVVDCNNQVKTAASYFNNS 189
            ||:|||:...||.|   :.|:.|...:|..|||.||:..|...|..|.        .||::|::|
  Rat   133 AVVKKGTGFQLNQL---QGKKSCHASLGWSAGWYVPLSVLLPSGSRET--------AAATFFSSS 186

  Fly   190 CAVYSLSDKHNPIGDNS--DKLCTLCTGKIPGG----RCSSADPYFGYEGAFKCLLE-KGDVAFL 247
            |.         |..|..  .:||.||:||   |    .|||.:|||||.||.|||.: .|||:|:
  Rat   187 CV---------PCADGKMFPRLCQLCSGK---GTDKCSCSSGEPYFGYWGALKCLQDGTGDVSFV 239

  Fly   248 RHSTVNEMLQTTEFKNIAPDTFELLCRDGRRASINDYRQCNWGQVPADAIVTSSARSFSDRKQYQ 312
            ||.||.|::.    :....|.:||||.|..|..:::|.||...:||:..:|   |||...::...
  Rat   240 RHLTVFEVMP----RKADRDQYELLCPDNTRRPVDEYEQCYLARVPSHVVV---ARSVDGKEDSI 297

  Fly   313 QFLKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSF 377
            |.|.|:|                           |..:|
  Rat   298 QELLRVA---------------------------QEHFG-------------------------- 309

  Fly   378 AEERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFTKYLGPAINFIYGI 442
                  :|.::|      |::|.|. :|| :|||.|::..|..:| .......|||  ...:..|
  Rat   310 ------KDKSST------FQLFGSP-HGK-DLLFTDAACGLLRVP-PKMDIGLYLG--YELLSAI 357

  Fly   443 RECPVPA-----MTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADIS 502
            |.....:     :..|...:.|..||.........     .|.|....:..:|:..:..|:||..
  Rat   358 RNLKRGSEDSRRVKWCAVGQQERAKCDHWSAVSGG-----ALACATEETPEDCIAAVMKGEADAV 417

  Fly   503 VFDAGDVYTGGLNYDLVPFMSEVY--------------NLGEPEYYVVAVAKEDDPDTELTYLKG 553
            ..|.|..|..| :..|||.:.|.|              |.....||||||.|:.|.......|:|
  Rat   418 NLDGGFAYIAG-HCGLVPGLGENYLSPHSSERLGSKCVNAALEGYYVVAVVKKSDVGITWNSLQG 481

  Fly   554 KNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYNTGVPYDSMC 618
            |.:|||.:.|:|||..||:|.        |.........|:|:..|.|||        .|...:|
  Rat   482 KKSCHTAVGTSAGWNVPMSLI--------YNQTGSCKFDEFFSGGCAPGA--------NPDSRLC 530

  Fly   619 DLCHGTS--YRYCRRDASEEYYGHTGAFRCLVEGGGHVAFMKHTTVMESTGGKRKEWWARNALND 681
            .||.|.:  ...|..:..|.|:|.:||.||||| .|.||||||.||:::|.||..|.||:...::
  Rat   531 ALCAGGNEPAHMCAANNDEGYHGSSGALRCLVE-KGDVAFMKHPTVLQNTDGKNPESWAKGLKHE 594

  Fly   682 DFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQLYGRKEVDAF 746
            ||||||.||||..:.:.:.|:|.:|..:||.:|      :.:::....:|...|:|:||...:..
  Rat   595 DFELLCLDGTRKPVTEAQNCHLDRVPNHAVFSR------KDKVDFVQRMLFNQQELFGRNGFEYR 653

  Fly   747 SFSMFSSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDFM 788
            .|.||.|  .|.||:|.|.|..|..: .||..|..|||..::
  Rat   654 MFQMFES--SHKDLLFSDDTECLSNL-QNKATYKTYLGPQYL 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf2	NP_524044.1	PBP2_transferrin	32..372	CDD:270247	107/354 (30%)
		PBP2_transferrin	450..792	CDD:270247	117/355 (33%)
Inhca	XP_038937483.1	PBP2_transferrin_N	39..361	CDD:270336	126/430 (29%)
		PBP2_transferrin_C	367..699	CDD:270335	117/358 (33%)