DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsf2 and depdc5

DIOPT Version :9

Sequence 1:	NP_524044.1	Gene:	Tsf2 / 39435	FlyBaseID:	FBgn0036299	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	XP_004910648.1	Gene:	depdc5 / 100498286	XenbaseID:	XB-GENE-980707	Length:	1608	Species:	Xenopus tropicalis

Alignment Length:	446	Identity:	77/446 - (17%)
Similarity:	133/446 - (29%)	Gaps:	137/446 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 YDEH-------KTTRMVWCTKSQAEQYKCQNLTVAIERDRALFDEVFLNLTCFMAYSADECIHHI 82
            :|:|       :|.:|..........::.....:.:.:.|.:.:.:.::|.|.    .::.:|.:
Frog   343 FDKHYINRNFDRTGQMSVVITPGVGVFQVDRSLMILTKQRMIDNGIGVDLVCM----GEQPLHAV 403

  Fly    83 DREKAHITTLDAGDVFTAGRYN-------SLIPIMQEKLEGGFADYQSVAVIK-------KGSLP 133
            ...|.| .....||......||       |......:.|...|.....:|..|       .|..|
Frog   404 PLFKLH-NRSSPGDSRLGDDYNIPHWINHSFYTSQSQPLNNSFTPRIKLAPRKTNSEKGRTGKDP 467

  Fly   134 DLNNLRDMRNKRVCFPWVGSLAGWIVPIHT-----------------LQREGGMEVVDCNNQVKT 181
            .:.:.::..|              .:||..                 .||......|. ..||:.
Frog   468 SIGSPKETEN--------------ALPIQVDYDAYDSQVFRLPGPSRAQRSITFRAVR-ETQVRK 517

  Fly   182 AASYFNNSCAVYSLSDKHNPI------GDNSD-----KLCTLCTGKIPGGRCSSADPYFGYEGAF 235
            ::..::.||:..|     .|.      ..|||     ||..:.....|......|....||...
Frog   518 SSCSYDTSCSPVS-----RPFTAEEGRSQNSDESSLGKLSNILLIPRPHLHQYEASSSLGYTST- 576

  Fly   236 KCLLEKGDVAFLRHSTVNEMLQTTEFKNIAPDTFE-------LLCRDG----RRASINDYRQCNW 289
            :..||:             |:::.:..:.||..|.       |..|.|    :||.||.:..
Frog   577 RDFLER-------------MIESQQRDSSAPGRFHVGSAESMLHVRPGGYHPQRALINPFAP--- 625

  Fly   290 GQVPADAIVTSSARSFSDR----------KQYQQFLKRIAELYSDGTRDDQ-------------- 330
            .::|..  :||:.|.:...          :.:.|..:.:|||...|.|:..
Frog   626 SRMPMK--LTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGMREASHSSAELLELAYHEA 688

  Fly   331 -SRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAEERNQQD 385
             .|..|......|.....|.  :|..|.|...|      |:....|:..|:.:..|
Frog   689 TGRHSGPRTPGENGSCGSNE--EFSCNTPINGQ------RNHNTGSNHREKESSDD 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsf2	NP_524044.1	PBP2_transferrin	32..372	CDD:270247	71/417 (17%)
		PBP2_transferrin	450..792	CDD:270247
		TR_FER	452..790	CDD:214514
depdc5	XP_004910648.1	IML1	126..407	CDD:371996	8/67 (12%)
depdc5	XP_004910648.1	DEP_DEPDC5-like	1184..1267	CDD:239896
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48076
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000