Protein Alignment Tsf2 and sxph

DIOPT Version :10

• Sequence 1: NP_524044.1
• Gene: Tsf2 / 39435
• FlyBaseID: FBgn0036299
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001107938.2
• Gene: sxph / 100000381
• ZFINID: ZDB-GENE-080204-110
• Length: 733
• Species: Danio rerio
• Alignment Length: 842
• Identity: 224/842 - (26%)
• Similarity: 352/842 - (41%)
• Gaps: 183/842 - (21%)

  Fly     6 VFVALVGALCFTLANAQHHYDEHKTTRMVWCTKSQAEQYKCQNLT---VAIERDRALFDEVFLNL 67
            |.|.|:..||...:..:         :|.||..|:|||.||..|.   ||:....|:  ..|..|
Zfish     7 VIVVLLLLLCSITSWGK---------KMRWCAVSEAEQKKCAELAKALVAVLPPAAV--TAFARL 60

  Fly    68 TCFMAYSADECIHHIDREKAHITTLDAGDVFTAGRYNSLIPIMQEKLEGGFADYQSVAVIKKGSL 132
            :|..|||..:||:.|...||.:.|||||:|::|.:...|..:.:|....| ....:|||::..|.
Zfish    61 SCVKAYSTADCINKIRDNKADLVTLDAGEVYSAVKQFGLTVVAKEIYRDG-GCILAVAVVRNNSS 124

  Fly   133 PDLNNLRDMRNKRVCFPWVGSLAGWIVPI-HTLQRE----GGMEVVDCNNQVKTAASYFNNSCAV 192
            .|   :|.::..|.|.......|||.:|: |.|.|.    ...|.:.     :..:::||.||..
Zfish   125 LD---MRSLQGSRSCHSGARWTAGWSLPLGHLLSRNLLPWAEDEPIS-----QAVSAFFNASCVP 181

  Fly   193 YSLSDKHNPIGDNSDKLCTLCTG-----KIPGGRC--SSADPYFGYEGAFKCLLE-KGDVAFLRH 249
            .:.:...|        ||.||.|     :.....|  |.::|::..:||.:||.. .||:||:.|
Zfish   182 GATTMAAN--------LCFLCKGQRSYIRQKNFHCETSHSEPFYHNQGALRCLQSGAGDIAFVDH 238

  Fly   250 STVNEMLQTTEFKNIAPDTFELLCRDGRRASINDYRQCNWGQVPADAIVTSSARSFSDRKQYQQF 314
            :.::.:.:..:      |...|||.||..|.::.:|.||.|:.|...:||    ..:.||..::|
Zfish   239 TALDSIDEREK------DELRLLCTDGSLAPLSSFRTCNLGRGPGGGVVT----RMNIRKIARKF 293

  Fly   315 LKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAE 379
            |  :|...|.|.|..:.|
Zfish   294 L--VAAQMSFGWRGRERR----------------------------------------------- 309

  Fly   380 ERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFTKYLGPAINFIYGIRE 444
                           :|::|||..:|..:|||:|.:..|:|:.| |...::.||  ::::..::.
Zfish   310 ---------------RFQLFESASFGGSDLLFRDVTEKLSVLME-DMDMSQVLG--LDYVALLKG 356

  Fly   445 CPVPAMTL-------CVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADIS 502
            ......:|       |..|..|..||.:...::|:    ..|:|.|..|..:|::.|:..:.|..
Zfish   357 LGHEGSSLEDSVVRWCCISHAEQKKCEQWAISIKS----DPLVCVKASSMSDCIEKIKRDEVDAV 417

  Fly   503 VFDAGDVYTGGLNYDLVPFMSEVYNLGE-----------------PEYYVVAVAKEDDPDTELTY 550
            ..||...:..| ...|||.::|.|  ||                 |..|.|||.:..........
Zfish   418 SLDATHAFIAG-KCGLVPVVTEYY--GEKCETSAGGGGHFESNELPPVYGVAVVRRSSKSLFFGS 479

  Fly   551 LKGKNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYNTGVPYD 615
            |..:.:||..:.:.|||..|:...:|........|:..:..:|.|.|.|:||...|
Zfish   480 LADRRSCHGHMYSPAGWVLPVRHTLSTEHNNSAPCEPNKVYSEVFWKGCLPGGQGN--------- 535

  Fly   616 SMCDLCHG----TSYRYCRRDASEEYYGHTGAFRCLV-----EGGGHVAFMKHTTVMESTGGKRK 671
             :|.:|.|    .:.:.|..:.:|.|||:.||.||||     :..|.||||:|..:..:......
Zfish   536 -LCKVCMGGTEEAATKRCADNHNERYYGNMGALRCLVGDPTGKSFGDVAFMEHHNLESNIERLNT 599

  Fly   672 EWWARNALNDDFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQ 736
            ..||...:..||||||:||:||.:..:|.||||.|..|.|:||       ..:.|.|..|....|
Zfish   600 SGWAEGWVTWDFELLCSDGSRAPLSQWKSCNLGAVPPNIVMTR-------PVLTARIYDLLMKSQ 657

  Fly   737 LYGRKEVDAFSFSMF-SSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDF-MRARRITDC 796
            .......|: .|.:| |...|..||:|:|.|:.|  :..:...|...||::| .:|..|.:|
Zfish   658 DTTEARPDS-GFHLFESQQYGESDLLFKDVTKCL--VHTSHMDYRTILGNEFCSQAESIFNC 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf2	NP_524044.1	PBP2_transferrin	32..372	CDD:270247	95/355 (27%)
		PBP2_transferrin	450..792	CDD:270247	107/376 (28%)
sxph	NP_001107938.2	None