Protein Alignment nst and PRM15

DIOPT Version :10

• Sequence 1: NP_648588.1
• Gene: nst / 39434
• FlyBaseID: FBgn0036298
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_014005.1
• Gene: PRM15 / 855321
• SGDID: S000004891
• Length: 622
• Species: Saccharomyces cerevisiae
• Alignment Length: 676
• Identity: 127/676 - (18%)
• Similarity: 193/676 - (28%)
• Gaps: 273/676 - (40%)

  Fly    11 FAREMYPKTSKET-------------------IQYGTAGFRGKAE-------FLDSVMFRMGVLA 49
            |.::..|||.:|.                   ||:||||.|.:.:       .|..:....|:..
Yeast    21 FKQDRNPKTIEEVTALCKKSDWNELHKRFDSRIQFGTAGLRSQMQAGFSRMNTLVVIQASQGLAT 85

  Fly    50 TLRSRY-----------------------------RGGSV------------------------- 60
            .:|.::                             :|..|
Yeast    86 YVRQQFPDNLVAVVGHDHRFHSKEFARATAAAFLLKGFKVHYLNPDHEFVHTPLVPFAVDKLKAS 150

  Fly    61 IGVMITASHNPEPDNGVK--------LVDPKGEMLEASWEAIATDLVNVSDQELEQQVAKIIKDN 117
            :||||||||||:.|||.|        ::.|....:..|.:|......||.|  .:..:.|.:|..
Yeast   151 VGVMITASHNPKMDNGYKVYYSNGCQIIPPHDHAISDSIDANLEPWANVWD--FDDVLNKALKQG 213

  Fly   118 NIDVTTSSQVFVGMDNRYHSPRLLKAVADGVIALKGNVKEYGIVTTPMLHYFVVAANTKEAYGKP 182
            .:              .|....:||...:.|   ..|:.|    ..|:         ..|...||
Yeast   214 KL--------------MYSREEMLKLYLEEV---SKNLVE----INPL---------KLEVKAKP 248

  Fly   183 TEEGYYDKLIKAFELLRNGRLENGNYRNSIIYDGANGVGARKMLQFIKRMKGTLNVTVINQGIGV 247
            .                            .:|...:|||.......:|:   ||
Yeast   249 W----------------------------FVYTPMHGVGFDIFSTIVKK---TL----------- 271

  Fly   248 GKINEDC---GADYVKV--QQSPPKSMPEDVKPYTR-------------------CVSVDGDADR 288
                  |   |.||:.|  ||:|..|.|....|...                   .|:.|.||||
Yeast   272 ------CLVEGKDYLCVPEQQNPDPSFPTVGFPNPEEKGALDIGINLAEKHDIDLLVANDPDADR 330

  Fly   289 VVYFFTD-DKGEFHLLDGDRIATLIAGYLMELVTQSEISLRLGLVQTAYANGASTDYIVDQLK-- 350
            ......| ..||:..|.|:.|..|.|.|..:.....:...: .:...|..|...:..::.::.
Yeast   331 FSVAVKDMQSGEWRQLTGNEIGFLFAFYEYQKYKSMDKEFQ-HVHPLAMLNSTVSSQMIKKMAEI 394

  Fly   351 --FPVSCVPTGVKHLHHKAL-------------EYDIGVYFEANGHGTIVFSDNAKATIAQVAQT 400
              |......||.|.:.::|:             |..||..|.|..|.    .|...|:|
Yeast   395 EGFHYEDTLTGFKWIGNRAILLEKKGYYVPFGFEEAIGYMFPAMEHD----KDGISASI------ 449

  Fly   401 KESAKTLLLLIDLINETVGDAISDMLLVETILNHKGWDVQDWISSYNDLPNRQLKVKVQD--RNV 463
                   :.|.......:...:..:.::|.  ..|.:.|....:.|..:||..:...:.|  |||
Yeast   450 -------VFLQAYCKWKIDHNLDPLNVLEN--GFKKYGVFKEYNGYYVVPNPTVTKDIFDYIRNV 505

  Fly   464 IETTDAERVCVKPEGLQTEIN-------------------------------QVVAKYKRG---- 493
            .....|.    .|..:..||.                               .|.|:...|
Yeast   506 YTPEGAS----YPSSIGEEIEVLYYRDLTTGYQSDTINHKPTLPVDPTSQMITVSARPSNGSENE 566

  Fly   494 --RSFVRPSGTEDVVRVYAEAATKED 517
              |..:|.||||..::||.||...|:
Yeast   567 HIRFTIRGSGTEPKLKVYIEACANEE 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nst	NP_648588.1	PGM3	25..529	CDD:100088	121/643 (19%)
PRM15	NP_014005.1	PGM2	52..596	CDD:100092	122/645 (19%)