DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nst and DRT101

DIOPT Version :9

Sequence 1:	NP_648588.1	Gene:	nst / 39434	FlyBaseID:	FBgn0036298	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_568359.2	Gene:	DRT101 / 831926	AraportID:	AT5G18070	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	554	Identity:	237/554 - (42%)
Similarity:	338/554 - (61%)	Gaps:	46/554 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EMYPKTSKETIQYGTAGFRGKAEFLDSVMFRMGVLATLRSRYRGGSVIGVMITASHNPEPDNGVK 78
            |::|......:.||||||||.|:.|:|.::|:|:|:.|||...|.:.:|:|||||||...|||:|
plant    14 ELFPIPQGVKLSYGTAGFRGDAKLLESTVYRVGILSALRSLKLGSATVGLMITASHNKVSDNGIK 78

  Fly    79 LVDPKGEMLEASWEAIATDLVNVSD-QELEQQVAKIIKDNNIDV---TTSSQVFVGMDNRYHSPR 139
            :.||.|.||...||..|..:.|.|. :||...:.|.::...|.:   ...::|::|.|.|.....
plant    79 VSDPSGFMLSQEWEPFADQIANASSPEELVSLIRKFMEKEEIAIGENNKGAEVWLGRDTRPSGES 143

  Fly   140 LLKAVADGVIALKGNVK-EYGIVTTPMLHYFVVAANTKEAYG-KPTEEGYYDKLIKAFELLRNGR 202
            ||:|...||.::.|:|. :.||:|||.||:.|.|.|.    | |.||..|::.|..:|..|.:..
plant   144 LLRAGEIGVGSILGSVAIDIGILTTPQLHWMVRAKNK----GLKATENDYFENLSTSFRCLIDLI 204

  Fly   203 LENGNYR---NSIIYDGANGVGARKMLQFIKRMKGT---LNVTVINQGIGVGKINEDCGADYVKV 261
            ..:||.:   :.::.|||||||.:|    |::::|:   |:|.:.|.|...|.:||..|||:|:.
plant   205 PSSGNDKLEISKLLVDGANGVGGQK----IEKLRGSLSNLDVEIRNTGRDGGVLNEGVGADFVQK 265

  Fly   262 QQSPPKSMP-EDVKPYTRCVSVDGDADRVVYFF--TDDKGEFHLLDGDRIATLIAGYLMELVT-- 321
            ::..|.... :||.  .||.|:||||||:|||:  :|...:..|||||:|.:|.|.::.|.:.
plant   266 EKVLPVGFGFKDVG--MRCASLDGDADRLVYFYIPSDSSEKVELLDGDKILSLFALFIKEQLNAL 328

  Fly   322 ---QSEISLRLGLVQTAYANGASTDYIVDQLKFPVSCVPTGVKHLHHKALEYDIGVYFEANGHGT 383
               :.....|||:|||||||||||||: ..|...|....|||||||.||.|:|||:|||||||||
plant   329 EDDEERKQSRLGVVQTAYANGASTDYL-KHLGLDVVFAKTGVKHLHEKAAEFDIGIYFEANGHGT 392

  Fly   384 IVFSDNAKATIAQVAQTKE-------------SAKTLLLLIDLINETVGDAISDMLLVETILNHK 435
            |:||::..:.:  |::.|:             :...|:.:.:|||:.||||:|.:||||.||.|.
plant   393 ILFSESFLSWL--VSKQKDLTAKGQGGSEEHKAVSRLMAVSNLINQAVGDALSGVLLVEVILQHL 455

  Fly   436 GWDVQDWISSYNDLPNRQLKVKVQDRNVIETTDAERVCVKPEGLQTEINQVVAKYKRGRSFVRPS 500
            ||.::.|...|.|||:||:||:|.||..:.||..|...::|.|:|..||..:.||.|||:|:|||
plant   456 GWSIEKWNELYKDLPSRQIKVEVPDRTAVVTTSEETEALRPMGIQDAINSEIKKYSRGRAFIRPS 520

  Fly   501 GTEDVVRVYAEAATKEDTDNLAYEVGLLVQKLAG 534
            ||||||||||||:|:||.|:||..|..||:...|
plant   521 GTEDVVRVYAEASTQEDADSLANSVAQLVKSFLG 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nst	NP_648588.1	PLN02895	6..539	CDD:215485	237/554 (43%)
nst	NP_648588.1	PGM3	25..529	CDD:100088	232/536 (43%)
DRT101	NP_568359.2	PLN02895	1..556	CDD:215485	237/554 (43%)
DRT101	NP_568359.2	PGM3	25..549	CDD:100088	232/536 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	70	1.000	Domainoid score	I3409
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9205
Inparanoid	1	1.050	399	1.000	Inparanoid score	I468
OMA	1	1.010	-	-		QHG56540
OrthoDB	1	1.010	-	-		D345441at2759
OrthoFinder	1	1.000	-	-		FOG0003921
OrthoInspector	1	1.000	-	-		oto3026
orthoMCL	1	0.900	-	-		OOG6_102413
Panther	1	1.100	-	-	LDO	PTHR45955
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840