Protein Alignment nst and PGM3

DIOPT Version :10

• Sequence 1: NP_648588.1
• Gene: nst / 39434
• FlyBaseID: FBgn0036298
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_054211587.1
• Gene: PGM3 / 5238
• HGNCID: 8907
• Length: 620
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 287/543 - (52%)
• Similarity: 364/543 - (67%)
• Gaps: 14/543 - (2%)

  Fly     1 MSINLRTVYAFAREMYPKTSKETIQYGTAGFRGKAEFLDSVMFRMGVLATLRSRYRGGSVIGVMI 65
            |.:...|.|:   .::.|.:...:||||||||.|||.||.||||||:||.|||: :..|.||||:
Human    55 MDLGAITKYS---ALHAKPNGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSK-QTKSTIGVMV 115

  Fly    66 TASHNPEPDNGVKLVDPKGEMLEASWEAIATDLVNVSDQELEQQVAKIIKDNNIDVTTSSQVFVG 130
            |||||||.|||||||||.||||..|||..||.|.|..:|::::.:..|.:...:::...:.|.:|
Human   116 TASHNPEEDNGVKLVDPLGEMLAPSWEEHATCLANAEEQDMQRVLIDISEKEAVNLQQDAFVVIG 180

  Fly   131 MDNRYHSPRLLKAVADGVIALKGNVKEYGIVTTPMLHYFVVAANTKEAYGKPTEEGYYDKLIKAF 195
            .|.|..|.:|.::|.|||..|.|...:||::|||.|||.|...||...|||.|.||||.||.|||
Human   181 RDTRPSSEKLSQSVIDGVTVLGGQFHDYGLLTTPQLHYMVYCRNTGGRYGKATIEGYYQKLSKAF 245

  Fly   196 -ELLRNGRLENGNYRNSIIYDGANGVGARKMLQFIKRMKGTLNVTVINQGIGVGKINEDCGADYV 259
             ||.:........|| |:..|.|||:||.|:.:........|:|.:.|.| ..||:|..||||:|
Human   246 VELTKQASCSGDEYR-SLKVDCANGIGALKLREMEHYFSQGLSVQLFNDG-SKGKLNHLCGADFV 308

  Fly   260 KVQQSPPKSMPEDVKPYTRCVSVDGDADRVVYFFTDDKGEFHLLDGDRIATLIAGYLMELVTQSE 324
            |..|.||:.|  ::|...||.|.||||||:||::.|..|.|||:|||:|||||:.:|.||:.:..
Human   309 KSHQKPPQGM--EIKSNERCCSFDGDADRIVYYYHDADGHFHLIDGDKIATLISSFLKELLVEIG 371

  Fly   325 ISLRLGLVQTAYANGASTDYIVDQLKFPVSCVPTGVKHLHHKALEYDIGVYFEANGHGTIVFSDN 389
            .||.:|:||||||||:||.|:.:.:|.||.|..||||||||||.|:|||||||||||||.:||..
Human   372 ESLNIGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTALFSTA 436

  Fly   390 AKATIAQVAQ-----TKESAKTLLLLIDLINETVGDAISDMLLVETILNHKGWDVQDWISSYNDL 449
            .:..|.|.|:     .:::||.|..:|||.|:..||||||||::|.||..||..||.|.:.|.||
Human   437 VEMKIKQSAEQLEDKKRKAAKMLENIIDLFNQAAGDAISDMLVIEAILALKGLTVQQWDALYTDL 501

  Fly   450 PNRQLKVKVQDRNVIETTDAERVCVKPEGLQTEINQVVAKYKRGRSFVRPSGTEDVVRVYAEAAT 514
            |||||||:|.||.||.||:|||..|.|.|||..||.:|.|||..|:|||||||||||||||||.:
Human   502 PNRQLKVQVADRRVISTTNAERQAVTPPGLQEAINDLVKKYKLSRAFVRPSGTEDVVRVYAEADS 566

  Fly   515 KEDTDNLAYEVGLLVQKLAGGVG 537
            :|..|:||:||.|.|.:||||:|
Human   567 QESADHLAHEVSLAVFQLAGGIG 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nst	NP_648588.1	PGM3	25..529	CDD:100088	277/509 (54%)
PGM3	XP_054211587.1	PGM3	76..581	CDD:100088	277/509 (54%)