Protein Alignment nst and Pgm2

DIOPT Version :10

• Sequence 1: NP_648588.1
• Gene: nst / 39434
• FlyBaseID: FBgn0036298
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001099477.2
• Gene: Pgm2 / 289632
• RGDID: 1306061
• Length: 620
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 99/544 - (18%)
• Similarity: 179/544 - (32%)
• Gaps: 186/544 - (34%)

  Fly    62 GVMITASHNPEPDNGVKLVDPKGEMLEASWEAIATDLVNVSDQELEQQVAKIIKDNNIDVTTSSQ 126
            |:||||||||:.|||.|:.          |:. ...:::..|:.:.|.:     :.|::
  Rat   167 GIMITASHNPKQDNGYKVY----------WDN-GAQIISPHDRGISQAI-----EENLE------ 209

  Fly   127 VFVGMDNRYHSPRLLKAVADGVIALKGNVKEYGIVTTPMLHYFVVAANTKEAYGKPTEEGYYDKL 191
                                                                   |..:.:.:.|
  Rat   210 -------------------------------------------------------PWPQAWDESL 219

  Fly   192 IKAFELLRN--GRLENGNYRNSIIYDGANGVGARKMLQFIKRMKGTLNVTVINQGIGVGKINEDC 254
            |.:..||.|  ..:.|..:.:...|.....|.....::|:.        |.::   |||  :|..
  Rat   220 IDSSSLLHNPSTSISNDYFEDLKKYCFHRTVNRESQVKFVH--------TSVH---GVG--HEFV 271

  Fly   255 GADYVKVQQSPPKSMPEDVKPYTRCVSV------------------------------DGDADRV 289
            .:.:.....:||:::|:...|.....:|                              |.||||:
  Rat   272 QSAFKAFDLNPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFELADKIKAKIVLANDPDADRL 336

  Fly   290 VYFFTDDKGEFHLLDGDRIATLIAGYLM---ELVTQSEISLRLGLVQTAYANGASTDYIVDQLKF 351
            ......|.||:.:..|:.:..|:..:|.   :...|.:.:|:...:.::..:......|..:..|
  Rat   337 AVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQGQSNLKDTYMLSSTVSSKILRAIALKEGF 401

  Fly   352 PVSCVPTGVKHLHHKALE-YDIG-----VYFEANGHGTIVF---SDNAKATIAQVAQTKESA-KT 406
            ......||.|.:.::|.: .|.|     .:.||.|:....|   .|...|.:.........| |.
  Rat   402 HFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELVSFLATKN 466

  Fly   407 LLLLIDL--INETVG------------DAISDMLLVETILNHKGWD-------------VQDWIS 444
            |.|.:.|  |....|            |..:...|.|.:.|:.|.:             |:|..:
  Rat   467 LSLSLQLKAIYLEYGYHITTASYFICHDQGTIQKLFENLRNYDGKNKYPKTCGKFEISAVRDLTT 531

  Fly   445 SY-NDLPNRQLKVKVQDRNVIETTDAERVCVKPEGLQTEINQVVAKYKRGRSFVRPSGTEDVVRV 508
            .| ::.|::        :.|:.|:.:.::..     .|.:|..||.       :|.||||..::.
  Rat   532 GYDSNQPDK--------KAVLPTSKSSQMIT-----FTFVNGGVAT-------MRTSGTEPKIKY 576

  Fly   509 YAEAAT---KEDTDNLAYEVGLLV 529
            |||...   ..|.:.|..|:..||
  Rat   577 YAELCAPPGNSDPEQLKRELDELV 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nst	NP_648588.1	PGM3	25..529	CDD:100088	97/542 (18%)
Pgm2	NP_001099477.2	PTZ00150	19..620	CDD:240294	99/544 (18%)