Protein Alignment nst and PGM2L1

DIOPT Version :9

• Sequence 1: NP_648588.1
• Gene: nst / 39434
• FlyBaseID: FBgn0036298
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_011543255.1
• Gene: PGM2L1 / 283209
• HGNCID: 20898
• Length: 643
• Species: Homo sapiens
• Alignment Length: 651
• Identity: 118/651 - (18%)
• Similarity: 199/651 - (30%)
• Gaps: 256/651 - (39%)

  Fly     3 INLRTVYAFAREMYPKTSKETIQYGTAGF------RGK----------AEFLDSVMFRMGVLATL 51
            ||..||....:.||....:....:...||      ||:          |:...:|:....|...|
Human   104 INDLTVIQSTQGMYKYLERCFSDFKQRGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYL 168

  Fly    52 RSRY-----------RGGSVIGVMITASHNPEPDNGVKLVDPKGEMLEASWEAIATDLVNVSDQE 105
            .|||           :..:|.|||||||||.:.|||.|:.          ||
Human   169 FSRYVPTPFVPYAVQKLKAVAGVMITASHNRKEDNGYKVY----------WE------------- 210

  Fly   106 LEQQVAKIIKDNNIDVTTSSQVFVGMDNRYHSPRLLKAVADGVIALKGNVKEYGIVTTPMLHYFV 170
                             |.:|:     ...|...:||.:.:.|....|:..:..:.|:|:..
Human   211 -----------------TGAQI-----TSPHDKEILKCIEECVEPWNGSWNDNLVDTSPLKR--- 250

  Fly   171 VAANTKEAYGKPTEE---GYYDKLIKAFELLRNGRLENGNYRNSIIYDGANGVGARKMLQFIKRM 232
                      .|.::   .|.:.|                                |.:.|.:.:
Human   251 ----------DPLQDICRRYMEDL--------------------------------KKICFYREL 273

  Fly   233 KGTLNVTVINQGI-GVGKINEDCGADYVKVQ-----QSPPKSMPEDVKP-----YTRC------- 279
            .....:..::... |||.       |||::.     ..||..:||...|     ..:|
Human   274 NSKTTLKFVHTSFHGVGH-------DYVQLAFKVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGE 331

  Fly   280 ------------------VSVDGDADRVVYFFTDDKGEFHLLDGDRIATLIAG------------ 314
                              ::.|.||||:......:.|.:.:..|:.:|.|...
Human   332 SVLELSLRLAEKENARVVLATDPDADRLAAAELQENGCWKVFTGNELAALFGWWMFDCWKKNKSR 396

  Fly   315 -------YLMELVTQSEISLRLGLVQTAYANGASTDY------IVDQLKFPVSCVPTGVKHLHHK 366
                   |::.....|:|...:.|.:..:.......:      |:|.|:       .|.:.|.
Human   397 NADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIIDLLE-------NGKEVLF-- 452

  Fly   367 ALEYDIGVYFEANGHGTIVFSD---NAKATIAQVAQTKESAK-TLLLLIDLINETVGDAIS---- 423
            |.|..||...     ||.|...   :|...:|::|...|:.. ||...:..:.|..|..||
Human   453 AFEESIGFLC-----GTSVLDKDGVSAAVVVAEMASYLETMNITLKQQLVKVYEKYGYHISKTSY 512

  Fly   424 ----DMLLVETILNH-KGWD----------------VQDWISSY-NDLPNRQLKVKVQDRNVIET 466
                :...:::|... :.:|                |:|..:.| :..||::..:.|...:.:.|
Human   513 FLCYEPPTIKSIFERLRNFDSPKEYPKFCGTFAILHVRDVTTGYDSSQPNKKSVLPVSKNSQMIT 577

  Fly   467 TDAERVCVKPEGLQTEINQVVAKYKRGRSFVRPSGTEDVVRVYAEAATKEDTDNLAYEVGLLVQK 531
            ...:..||                    :.:|.||||..::.|||.....|..:.|    ||.::
Human   578 FTFQNGCV--------------------ATLRTSGTEPKIKYYAEMCASPDQSDTA----LLEEE 618

  Fly   532 L 532
            |
Human   619 L 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nst	NP_648588.1	PLN02895	6..539	CDD:215485	116/648 (18%)
		PGM3	25..529	CDD:100088	110/624 (18%)
PGM2L1	XP_011543255.1	PTZ00150	24..642	CDD:240294	118/651 (18%)
		PGM2	85..628	CDD:100092	118/651 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900