Protein Alignment eIF2beta and eif-2beta

DIOPT Version :9

• Sequence 1: NP_524043.1
• Gene: eIF2beta / 39433
• FlyBaseID: FBgn0004926
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_492209.1
• Gene: eif-2beta / 172584
• WormBaseID: WBGene00010560
• Length: 250
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 136/307 - (44%)
• Similarity: 173/307 - (56%)
• Gaps: 68/307 - (22%)

  Fly     3 AED-GFDPTLLKKKKKKKTTFDLDAALGLEDDTKKEDPQDEASAEGGAAAEEDNLDLESFGKKKK 66
            |:| |.|   |.||||.|....:|.              |:|..|.|..|.||.|...:.|.|||
 Worm     2 ADDLGLD---LGKKKKSKKVIKIDG--------------DDAPVETGVEAVEDGLGELNLGAKKK 49

  Fly    67 KKKKPFNMDEIEAAIPSFGGDDVAASEEPEEEEINLDMDFSMAKKKKKSKKKELDELFADQADDD 131
            ||            .|...|::|.     ||:...|::...
 Worm    50 KK------------TPKTAGEEVV-----EEKVPTLEIGIG------------------------ 73

  Fly   132 KSEDKENDEDNSSTWFGSDRDYTYDELLKRVFEIILDKNPDMAAGRKPKFVMRPPQVLRVGTKKT 196
                .:|..|....|    .||||:|.|..|::::.|||||. ||.|.||.::.|:|.|.|:|||
 Worm    74 ----AQNLIDAKGAW----PDYTYEEALTLVYQVMKDKNPDF-AGDKKKFAIKLPEVARAGSKKT 129

  Fly   197 SFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCH 261
            :|:||::|.:.:.|..||:|.||||||||:||:||:..||:|||:|.||.|:|||:||||||.||
 Worm   130 AFSNFLEICRLMKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFESVLRKYIKEYVMCH 194

  Fly   262 TCRSPETILQKDTRLFFLQCESCGSRCSVASIKSGFQAVTGKRAAIR 308
            ||:||||.|.||||||||||.:|||||||.:|||||:||.|||||||
 Worm   195 TCKSPETQLTKDTRLFFLQCTNCGSRCSVTAIKSGFKAVVGKRAAIR 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2beta	NP_524043.1	eIF2B_5	178..287	CDD:214764	69/108 (64%)
eif-2beta	NP_492209.1	eIF2B_5	111..220	CDD:214764	69/108 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I2631
eggNOG	1	0.900	-	-		E1_COG1601
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	229	1.000	Inparanoid score	I2208
Isobase	1	0.950	-	0	Normalized mean entropy	S817
OMA	1	1.010	-	-		QHG55888
OrthoDB	1	1.010	-	-		D1178655at2759
OrthoFinder	1	1.000	-	-		FOG0004439
OrthoInspector	1	1.000	-	-		oto19274
orthoMCL	1	0.900	-	-		OOG6_101265
Panther	1	1.100	-	-	LDO	PTHR23001
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R592
SonicParanoid	1	1.000	-	-		X3723
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.860