DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gcn5 and RSC4

DIOPT Version :9

Sequence 1:	NP_648586.2	Gene:	Gcn5 / 39431	FlyBaseID:	FBgn0020388	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_012933.4	Gene:	RSC4 / 853877	SGDID:	S000001716	Length:	625	Species:	Saccharomyces cerevisiae

Alignment Length:	318	Identity:	74/318 - (23%)
Similarity:	113/318 - (35%)	Gaps:	86/318 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   500 YQLPEMPREYISQLVFDTKH---------KTL-ALIKENQPIGGICFRPF---PSQGFTEIVFCA 551
            |..|..|:   |:|..|..|         .|| .||.:.:.|    |:.|   ||:.|....:..
Yeast    38 YNAPLNPK---SELFLDDWHIPKFNRFISFTLDVLIDKYKDI----FKDFIKLPSRKFHPQYYYK 95

  Fly   552 VTMSEQVKGYGTHLMNHLK--DYSIQRGIKHLLTFADCDAIGYFKKQGFSKDIKLARPVYAGYIK 614
            :.....:        |.:|  ||..:.|                 ...|..|::|.......| .
Yeast    96 IQQPMSI--------NEIKSRDYEYEDG-----------------PSNFLLDVELLTKNCQAY-N 134

  Fly   615 EYDSATLMHCELHPSIVNTQFIAVIRSQSEILKELIAQRHNEV-QKVRPGLTCFKEGLPVIPVES 678
            ||||.          ||......|:..:.|:||....:|:..: .:|:..|..:...| |...|.
Yeast   135 EYDSL----------IVKNSMQVVMLIEFEVLKAKNLKRNYLINSEVKAKLLHYLNKL-VDATEK 188

  Fly   679 IPGLREIGWKPQNRPARSSRPLEESTDPEKLATSFASVLQSVRQHTTAWPFLRPVTAAEVPDYYD 743
            ......:|       |.|.:.|:   |..||:.                ||:..|...|:|:||:
Yeast   189 KINQALLG-------ASSPKNLD---DKVKLSE----------------PFMELVDKDELPEYYE 227

  Fly   744 HIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYF 801
            .:..||.|..:.:.|:.|.|.....|:.||..:|.|...:|.|....|:.|.:|..||
Yeast   228 IVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYKDATTLTNYF 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997
		COG5076	451..807	CDD:227408	74/318 (23%)
		Acetyltransf_1	526..598	CDD:278980	11/76 (14%)
		Bromo_gcn5_like	708..808	CDD:99941	27/94 (29%)
RSC4	NP_012933.4	COG5076	40..423	CDD:227408	73/316 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900