Protein Alignment Gcn5 and SPT7

DIOPT Version :9

• Sequence 1: NP_648586.2
• Gene: Gcn5 / 39431
• FlyBaseID: FBgn0020388
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_009637.1
• Gene: SPT7 / 852373
• SGDID: S000000285
• Length: 1332
• Species: Saccharomyces cerevisiae
• Alignment Length: 783
• Identity: 133/783 - (16%)
• Similarity: 243/783 - (31%)
• Gaps: 309/783 - (39%)

  Fly    61 VPAEGTRQNSLQRIQQRKQKVFN------LPVPQKLAKLSMYSACQSEGCRCTGWK--------- 110
            :|.:..::.:.:.:.:..:|:||      ....|:|..|....:..||..:...|.
Yeast     5 IPIKNYQRTNAKALLKLTEKLFNKNFFDLYLTSQQLVVLEYLLSISSEEDKLKAWDYFLKGNIAL 69

  Fly   111 --------TPQENRH-----------RDVESSYCPEFNEECRNTSCRHSLRSHIAHLDN-ISSSS 155
                    |.:|..|           .||.|....:.|....|||.     |:..|::| |....
Yeast    70 NVEKSFPLTQEEEHHGAVSPAVDTRSDDVSSQTIKDNNNTNTNTSI-----SNENHVENEIEDKG 129

  Fly   156 MNELLGAIIDMENLFMSMQRVEDEDTKKVYQYLFRLLRQCVLTRQQAVIRGPLGDPPFETPCITK 220
            .|    ||.:.:|.      |.::::..|.:.||:|
Yeast   130 DN----AIANEDNF------VNNDESDNVEEDLFKL----------------------------- 155

  Fly   221 AVLSLVFYKYNHLSTPELQTMTEVAKTFLNFLNHYNFESPSTR-RGDLTHEDASNYKINYTRWLV 284
                            :|:.:.:              :...|| .|:|      :.||.|..|
Yeast   156 ----------------DLEDLKQ--------------QISGTRFIGNL------SLKIRYVLW-- 182

  Fly   285 FCHVPAFCNSLRQCETSLVFGRTLLRTVFQCMSQQLKKKCISERDRFPEDKRSIITLMPKFLETL 349
                        ||....::                   |  :|:.|.::.
Yeast   183 ------------QCAIDYIY-------------------C--DRNEFGDEN-------------- 200

  Fly   350 RAELLKDDSPIWDTSYRPSNSFVIQQRKRNQEVANVPIGPSAASIGGNKRTSVGEPLHKRIKKEP 414
                        ||.|    :.:..:.|..:|            ||.|::....|.:.|..:.|.
Yeast   201 ------------DTEY----TLLDVEEKEEEE------------IGKNEKPQNKEGISKFAEDED 237

  Fly   415 TDRPSSENLDDLPADVVMRAMKSVSESKTTNKAEILFPVNVS--RDENVKAEEQKRAIEFHVVGN 477
            .| ...||.|:...||     |:|.:.          |.|:.  ...|::.::::|.    |:..
Yeast   238 YD-DEDENYDEDSTDV-----KNVDDP----------PKNLDSISSSNIEIDDERRL----VLNI 282

  Fly   478 SLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIKENQPIGGICFRPFPSQ 542
            |::|                                      :||:.:|.|.
Yeast   283 SISK--------------------------------------ETLSKLKTNN------------- 296

  Fly   543 GFTEIVFCAVTMSEQVKGYGTHLMNHLKDYSIQRGIKHLLTFADCDAIGYFKKQGFSKDIKLA-- 605
                        .|::.| ..:.:.|..:|..:..||.|........|...||:....|::.|
Yeast   297 ------------VEEIMG-NWNKIYHSFEYDKETMIKRLKLEESDKMIEKGKKKRSRSDLEAATD 348

  Fly   606 ---------RPVYAGYIKEYDSATLMHC-ELHPSIVNTQFIAVIRSQSEILKELIAQRHNEVQKV 660
                     .|.....:...:.:|.... ...|...|......:..::..||.|::.  .:.:|.
Yeast   349 EQDRENTNDEPDTNQKLPTPEGSTFSDTGNKRPKQSNLDLTVNLGIENLSLKHLLSS--IQQKKS 411

  Fly   661 RPGLTCFKEGLPVIPVESIPGLREIGWKPQNRPARSSRPLEESTDPEKLATSFASVLQSVRQHTT 725
            :.|::.::....::.|               |..||....:|....|:|..:...|:..:|.:|.
Yeast   412 QLGISDYELKHLIMDV---------------RKNRSKWTSDERIGQEELYEACEKVVLELRNYTE 461

  Fly   726 -AWPFLRPVTAAEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTE 789
             :.|||..|:..|.|:|:..||..|||.|:.::||...|.:::.|:.|:..|:.||..|||..:.
Yeast   462 HSTPFLNKVSKREAPNYHQIIKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTYNSDPSH 526

  Fly   790 YYR 792
            :.|
Yeast   527 FLR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997	43/284 (15%)
		COG5076	451..807	CDD:227408	67/357 (19%)
		Acetyltransf_1	526..598	CDD:278980	12/71 (17%)
		Bromo_gcn5_like	708..808	CDD:99941	29/86 (34%)
SPT7	NP_009637.1	COG5076	282..680	CDD:227408	62/329 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810