DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gcn5 and BDF2

DIOPT Version :9

Sequence 1:	NP_648586.2	Gene:	Gcn5 / 39431	FlyBaseID:	FBgn0020388	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_010213.1	Gene:	BDF2 / 851488	SGDID:	S000002228	Length:	638	Species:	Saccharomyces cerevisiae

Alignment Length:	135	Identity:	35/135 - (25%)
Similarity:	67/135 - (49%)	Gaps:	12/135 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   677 ESIPGLREIGWKPQNRPARSSRPLEESTDPEKL----ATSFASVLQSVRQHTTAWPFLRPV--TA 735
            ||.|. ..:|.:.:..||     ||...:.|:|    :....|.:::.::...|.|||:||  .|
Yeast   108 ESFPE-HPLGLERETEPA-----LEAEMEAEELPPHQSKYLLSSIKATKRLKDARPFLKPVDPIA 166

  Fly   736 AEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERY 800
            ..:|.|:::::.||||..:..:|:...|.:.....:|...:..||..:|.|::.....|..:::|
Yeast   167 LNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKY 231

  Fly   801 FQTKM 805
            |:.|:
Yeast   232 FEKKL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997
		COG5076	451..807	CDD:227408	35/135 (26%)
		Acetyltransf_1	526..598	CDD:278980
		Bromo_gcn5_like	708..808	CDD:99941	26/104 (25%)
BDF2	NP_010213.1	COG5076	55..378	CDD:227408	35/135 (26%)
		Bromodomain	<344..419	CDD:413371
		Lebercilin	<472..>537	CDD:406132
		BET	521..576	CDD:407211
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810