DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gcn5 and Brd8

DIOPT Version :9

Sequence 1:	NP_648586.2	Gene:	Gcn5 / 39431	FlyBaseID:	FBgn0020388	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_651685.2	Gene:	Brd8 / 43460	FlyBaseID:	FBgn0039654	Length:	872	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	45/185 - (24%)
Similarity:	62/185 - (33%)	Gaps:	59/185 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   640 RSQSEILKE--LIAQRHNEVQKVRPGLTCFKEGLPVIPVESIPGLREIGWKPQNRPARSSRPLEE 702
            ||:|.::.:  ..|..|:..:..|  ..|  ...|||  :|||          |.||.|     |
  Fly   677 RSESPMVDDDATTASDHSTARSTR--RRC--SSTPVI--DSIP----------NSPASS-----E 720

  Fly   703 STDP--EKLATS---FASVLQSVRQHTTAWPFLRPVTAAEVPDYYDHIKYPMDLKTMGERLKKGY 762
            .||.  |..|.|   |.|:...:.....|.||.||........:.|....|||..|:...:..|:
  Fly   721 HTDDRRETRAASKKLFLSIYAMLLDSKHAAPFKRPFHDEHAQRHADLCLRPMDFPTIKRNIDSGF 785

  Fly   763 ----------------------------YQTRRLFMADMARIFSNCRFYNSPDTE 789
                                        ::|.|||:.|...|   ..|...||.:
  Fly   786 IRSLSELHRDVLLMAHNVLVAYKPHTAQHKTARLFVQDCQAI---KEFSQLPDVQ 837

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997
		COG5076	451..807	CDD:227408	45/185 (24%)
		Acetyltransf_1	526..598	CDD:278980
		Bromo_gcn5_like	708..808	CDD:99941	24/113 (21%)
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408
		PHA03249	402..>582	CDD:223023
		Bromo_brd8_like	729..833	CDD:99939	22/106 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810