DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gcn5 and Brd4

DIOPT Version :9

Sequence 1:	NP_648586.2	Gene:	Gcn5 / 39431	FlyBaseID:	FBgn0020388	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_001094373.1	Gene:	Brd4 / 362844	RGDID:	1307282	Length:	1403	Species:	Rattus norvegicus

Alignment Length:	131	Identity:	47/131 - (35%)
Similarity:	72/131 - (54%)	Gaps:	10/131 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   688 KPQNRPARSSR-PLEESTDPEK-------LATSFASVLQSVRQHTTAWPFLRPVTAAE--VPDYY 742
            :||:..|.|:. |..|:::|.|       |......||:::.:|..||||.:||.|.:  :||||
  Rat    34 QPQSANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYY 98

  Fly   743 DHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQTKMRE 807
            ..||.|||:.|:.:||:..||...:..:.|...:|:||..||.|..:....|.:||:.|..|:.|
  Rat    99 KIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163

  Fly   808 L 808
            |
  Rat   164 L 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997
		COG5076	451..807	CDD:227408	45/128 (35%)
		Acetyltransf_1	526..598	CDD:278980
		Bromo_gcn5_like	708..808	CDD:99941	38/108 (35%)
Brd4	NP_001094373.1	Bromo_Brdt_I_like	58..164	CDD:99929	37/105 (35%)
		Bromo_Brdt_II_like	354..455	CDD:99930
		BET	610..674	CDD:293640
		BRD4_CDT	1361..1403	CDD:293710
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810