DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gcn5 and brd3a

DIOPT Version :9

Sequence 1:	NP_648586.2	Gene:	Gcn5 / 39431	FlyBaseID:	FBgn0020388	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_001116861.1	Gene:	brd3a / 327372	ZFINID:	ZDB-GENE-030131-6141	Length:	683	Species:	Danio rerio

Alignment Length:	200	Identity:	54/200 - (27%)
Similarity:	88/200 - (44%)	Gaps:	19/200 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   628 PSIVNTQFIAVI----RSQSEILKELIAQRHNEVQKVRPGLTCFKEGLPVIPVE----SIPGLRE 684
            |::.||...|||    .||..:.|:.:.::.:........:|..:...|...:|    .:...||
Zfish   200 PAVQNTTAAAVIPSMPPSQPTVKKKGVKRKADTTTPTTSAITASRSQSPTPILEGKQSKVAARRE 264

  Fly   685 IGWKPQNRPARSSRPLE---------ESTDPEKLATSFASVLQSVRQHTTAWPFLRPV--TAAEV 738
            ...:|...|.:.....|         ..::..|........:.|.:....||||.:||  .|.|:
Zfish   265 STGRPIKPPKKDFEDGELGVHGGKKGRLSEQLKYCDVILKEMLSKKHAAYAWPFYKPVDAEALEL 329

  Fly   739 PDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQT 803
            .||:|.||:||||.|:.:::....||..:.|.||:..:||||..||.||.|....|..|:..|:.
Zfish   330 HDYHDIIKHPMDLSTVKKKMDSREYQDAQTFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 394

  Fly   804 KMREL 808
            :..::
Zfish   395 RFAKM 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997
		COG5076	451..807	CDD:227408	54/197 (27%)
		Acetyltransf_1	526..598	CDD:278980
		Bromo_gcn5_like	708..808	CDD:99941	37/101 (37%)
brd3a	NP_001116861.1	Bromo_Brdt_I_like	30..136	CDD:99929
		Bromo_Brdt_II_like	295..396	CDD:99930	37/100 (37%)
		BET	574..638	CDD:293640
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810