DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gcn5 and F22F1.3

DIOPT Version :9

Sequence 1:	NP_648586.2	Gene:	Gcn5 / 39431	FlyBaseID:	FBgn0020388	Length:	813	Species:	Drosophila melanogaster
Sequence 2:	NP_509376.2	Gene:	F22F1.3 / 184851	WormBaseID:	WBGene00017715	Length:	245	Species:	Caenorhabditis elegans

Alignment Length:	280	Identity:	48/280 - (17%)
Similarity:	86/280 - (30%)	Gaps:	118/280 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 LKKKC---ISERDRFPEDKRSIITLMPKFLETLRAELLKDDSPIWDTSYRPSNSFVIQQRKRNQE 381
            ::||.   :..:|.:..:...||..|.|.|::                 ||..|:       ...
Worm    56 MEKKSFEKVQTKDEYYAELARIILSMQKHLQS-----------------RPKGSY-------EDP 96

  Fly   382 VANVPIGPSAASIGGNKRTSVGEPLHKRIKKEPTDRPSSENLDDLPADVVMRAMKSVSESKTTNK 446
            .:|:|                               ||.|..|.|......|           ::
Worm    97 YSNIP-------------------------------PSHELADFLGLSAQER-----------DE 119

  Fly   447 AEILFPVNVSRDENVKAEEQKRAIEFHVVGNSLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYIS 511
            ..:|.|..:.: .|.|:...:| |..||        :||      |||.|   :..|:....|..
Worm   120 FYLLHPHRLLK-PNAKSRITRR-IRIHV--------IDK------LGLML---FPAPDQNAYYDG 165

  Fly   512 QLVFDTKHKTLALIKENQPIGGICFRPFPSQGFTEIVFC----------AVTMSEQVKGYGTHLM 566
            ::.        .:|::        .|...::.|.|.:.|          |..:.:.:|..|.|.:
Worm   166 RMD--------RIIRK--------LRNLEAEAFRECIDCDDYYNLASIKAYKLHKTMKKNGEHYV 214

  Fly   567 NHLKDYSIQRGIKHLLTFAD 586
            :|    .::....|:.|.|:
Worm   215 DH----EVKYPAIHIYTSAN 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997	0/1 (0%)
		COG5076	451..807	CDD:227408	28/146 (19%)
		Acetyltransf_1	526..598	CDD:278980	12/71 (17%)
		Bromo_gcn5_like	708..808	CDD:99941
F22F1.3	NP_509376.2	KIX	7..87	CDD:280354	8/30 (27%)
F22F1.3	NP_509376.2	KIX	128..208	CDD:280354	20/114 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900