Protein Alignment tral and LSM14A

DIOPT Version :9

• Sequence 1: NP_001261775.1
• Gene: tral / 39430
• FlyBaseID: FBgn0041775
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_005258776.1
• Gene: LSM14A / 26065
• HGNCID: 24489
• Length: 487
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 194/622 - (31%)
• Similarity: 249/622 - (40%)
• Gaps: 198/622 - (31%)

  Fly     1 MSGGLPELGSKISLISKADIRYEGRLYTVDPQECTIALSSVRSFGTEDRDTQFQIAPQSQIYDYI 65
            ||||.|.:||||||||||:|||||.|||:|.:..|:||:.|||||||||.|...|.|:.::::||
Human     1 MSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYI 65

  Fly    66 LFRGSDIKDIRVVN----NHTLPHHNDPAIMQAQLQNGPPQMPQHFPMPSGMSGPPQQQQVPSQQ 126
            :||||||||:.|..    ..:||  .||||:|:.|.:.....     ...|..||..:....||.
Human    66 IFRGSDIKDLTVCEPPKPQCSLP--QDPAIVQSSLGSSTSSF-----QSMGSYGPFGRMPTYSQF 123

  Fly   127 PPQMPSGGGSGGAGGAGAPGGGGPGYGNGNPFG----NLGGPNLANMVGNA--------GGSLAP 179
            .|....|...|..|.||:         :...||    |.|....::.||:|        ...|:.
Human   124 SPSSLVGQQFGAVGVAGS---------SLTSFGTETSNSGTLPQSSAVGSAFTQDTRSLKTQLSQ 179

  Fly   180 GSGAPGSGPFMHIGGNQQQPKPQQQKQPISVLDMLAGASRSTTPISLIVSPTAELTQQQQLHQQQ 244
            |..:|...|.      ::.|..:|..|..|.......|....:|:|....|:|          .|
Human   180 GRSSPQLDPL------RKSPTMEQAVQTASAHLPAPAAVGRRSPVSTRPLPSA----------SQ 228

  Fly   245 NAGQGGNGRDAGHKRQNHQQQQNQQHQQRGGPSHNNMQQQQQRGGGSGTDFYNQQRDRRDSGRQM 309
            .||                  :||:|  |....|...:.:            |:|. |.|:.||:
Human   229 KAG------------------ENQEH--RRAEVHKVSRPE------------NEQL-RNDNKRQV 260

  Fly   310 DNNYSNNYNNNNNNQRNRGGGNGMQQQQRGGNGGSGGGGGNGGGNNPAWNMHRGNQNSNNMMNMR 374
                                ..|.....|.|.||..||.|
Human   261 --------------------APGAPSAPRRGRGGHRGGRG------------------------- 280

  Fly   375 NRGMGSRGPMRPNQGYRPQSANNQNKPRNKIKFEGDFDFEQANNKF--EEL-RSQLAKLKVAEDG 436
            ..|:...|||                     |||.|||||.||.:|  ||: |....|||:.||.
Human   281 RFGIRRDGPM---------------------KFEKDFDFESANAQFNKEEIDREFHNKLKLKEDK 324

  Fly   437 APKPATNATAATATATNEQVGEKVEGVHTLNGETDKKDDSGNETGAGEHEPEEDDVA---VCYDK 498
            ..|.                 ||     .:|||  .|.|||.:|...|...:|:|..   ..|||
Human   325 LEKQ-----------------EK-----PVNGE--DKGDSGVDTQNSEGNADEEDPLGPNCYYDK 365

  Fly   499 TKSFFDNISCEAAQDRSKNKKNDWRQERKLNTETFGVSSTRRGSSYRGRNQYYNNNGNGGINSGY 563
            ||||||||||    |.::.::..|.:||:||.||||:.....    |||..|   .|.||:  |:
Human   366 TKSFFDNISC----DDNRERRPTWAEERRLNAETFGIPLRPN----RGRGGY---RGRGGL--GF 417

  Fly   564 GGAPGYNRNNYRMGGGGGNFRNRSNNRNNGGGRGGNG 600
            .|..|      |.||.||.|......|  ||.|||.|
Human   418 RGGRG------RGGGRGGTFTAPRGFR--GGFRGGRG 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tral	NP_001261775.1	LSm14_N	4..77	CDD:212483	46/72 (64%)
		FDF	406..536	CDD:286601	56/135 (41%)
LSM14A	XP_005258776.1	LSm14_N	4..77	CDD:212483	46/72 (64%)
		FDF	291..399	CDD:286601	56/135 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154109
Domainoid	1	1.000	97	1.000	Domainoid score	I7273
eggNOG	1	0.900	-	-		E1_KOG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1569369at2759
OrthoFinder	1	1.000	-	-		FOG0001497
OrthoInspector	1	1.000	-	-		otm40357
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13586
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2277
SonicParanoid	1	1.000	-	-		X1222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.930