DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sti and AT3G23310

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_188973.2	Gene:	AT3G23310 / 821911	AraportID:	AT3G23310	Length:	568	Species:	Arabidopsis thaliana

Alignment Length:	585	Identity:	163/585 - (27%)
Similarity:	270/585 - (46%)	Gaps:	149/585 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RRSIVPVSTTSAAVAEAICREGLLDAFCLLYNECDKDTLKKRDRNIAEFVNKFRPIIEETRKLRV 108
            ||.::.....:|.|:|                |..|:.||..::...|::.:        ::.::
plant    75 RRDMLENKLAAAEVSE----------------EEQKNLLKDLEKKETEYMRR--------QRHKM 115

  Fly   109 NADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVV----TTSQVKEERDIMSIRNSEWL 169
            ..|||...|:||:|.||.|.:..|:.|.::|||||:|||.:    ....||.||::::..:|..:
plant   116 GTDDFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNCI 180

  Fly   170 INLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIK 234
            :.|..:|||.:.|||:|||:||||:::|:.|.....||.||||:.|..:|:.::|:..|:|||||
plant   181 VKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLAIESIHKHNYIHRDIK 245

  Fly   235 PENILIDRFGHIKLADFGNAAALD----------------------------------------- 258
            |:|:|:||.||:||:|||....||
plant   246 PDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQSDGRPVAPRRTRSQMEQLQNW 310

  Fly   259 -RDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHE 322
             |:..:|:.|.||||||||||:|       |.|...     :.||:||:|.|.||::....||:.
plant   311 QRNRRMLAYSTVGTPDYIAPEVL-------LKKGYG-----MECDWWSLGAIMYEMLVGFPPFYS 363

  Fly   323 DNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYE---RIKNHPFFS 384
            |....|..||:      :.|..:.||.::::|...::||..|:.|..:|:..:   .||.||:||
plant   364 DEPMTTCRKIV------NWKNYLKFPDEVRLSPEAKDLICRLLCNVEQRIGTKGANEIKEHPWFS 422

  Fly   385 EIPWGSIRSQVPPIIPTVRSDDDTSNFE-----DGIRHKTRREQGVAKKSLTTNMKSNDFSGKDL 444
            .:.|..:.......||.|..:.||.|||     |....||.: .|..:|.|         |.||:
plant   423 GVEWEKLYQMKAAFIPQVNDELDTQNFEKFEETDKQVPKTPK-SGPWRKML---------SSKDI 477

  Fly   445 PFIGYSFVHMEKSAISATTDEKLQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDNKSQVV 509
            .|:||::.::|                               ::..|.|.....|:|...|.:
plant   478 NFVGYTYKNVE-------------------------------IVNHDQLPGIAELKKKSTKPK-- 509

  Fly   510 ADAKMEIKKLQQIIKEKTMELTTCK--TQIKTLQSSAKIDEEMWSKKEATITDLLRLNRQKYEEA 572
               :..||.|   .::::...||..  :.:|.|.:..::.|:  ..|.::.::.|..:..:::.|
plant   510 ---RPSIKSL---FEDESASSTTSHQGSFMKLLPTQIEVPEK--EDKSSSSSETLSSSTTRFDNA 566

Fly 573 572
plant 567 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	136/394 (35%)
		S_TKc	113..383	CDD:214567	111/318 (35%)
		Smc	487..1222	CDD:224117	16/88 (18%)
		CNH	1503..1774	CDD:279162
AT3G23310	NP_188973.2	STKc_NDR_like	118..485	CDD:270750	136/394 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920