DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sti and AT2G20470

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_001318254.1	Gene:	AT2G20470 / 816567	AraportID:	AT2G20470	Length:	569	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	169/566 - (29%)
Similarity:	264/566 - (46%)	Gaps:	134/566 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KGAGVCAKPAGSASGSGIPASTRRSIVPV------STTSAAVAEA-------------ICREGLL 67
            |||      :|.|.|.|...|.....|..      :||...||.|             |.:|...
plant    20 KGA------SGGAGGGGSNGSADEHNVETDEEAVSNTTKQKVAAAKQYIENHYKEQMKILQERKE 78

  Fly    68 DAFCLLYNECDKDTLKKRDRNIAEFVNKFRPIIEETRKLR-----VNADDFLIKTLIGQGYFGNV 127
            ....|.....|.|..::...|:.:|:.|     :||..:|     :...||.:.|:||:|.||.|
plant    79 RRSMLEQKLADADVSEEDQNNLLKFLEK-----KETEYMRLQRHKLGVADFDLLTMIGKGAFGEV 138

  Fly   128 HLVVERQTNDIYAMKKIKKSVV----TTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEY 188
            .:..|:.|..:|||||:||:.:    ....|:.||::::..:|.:::.|..:|||:|:|||||||
plant   139 RVCREKTTGQVYAMKKLKKAEMLRRGQVEHVRAERNLLAEVDSNYIVKLYCSFQDDDHLYLVMEY 203

  Fly   189 MPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGN 253
            :||||:::|:.|.....|:.|:||:||..:|:.::|...|:||||||:|:|:||:||::|:|||.
plant   204 LPGGDMMTLLMRKDTLTEEEAKFYVAETVLAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGL 268

  Fly   254 AAALD--------------------------------------RDGHVLSLSPVGTPDYIAPELL 280
            ...||                                      |:...|:.|.||||||||||:|
plant   269 CKPLDCSAIGENDFSNNSNGSTEQEAGSTAPKRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVL 333

  Fly   281 QTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELI 345
                   |.|...     :.||:||:|.|.||::....||:.|:...|..||::.  :||||
plant   334 -------LKKGYG-----MECDWWSLGAIMYEMLVGYPPFYSDDPMSTCRKIVNW--KSHLK--- 381

  Fly   346 SFPADLKVSVNYRNLIESLVTNPSKRL---SYERIKNHPFFSEIPWGSIRSQVPPIIPTVRSDDD 407
             ||.:..:|...::||.||:.:..:||   ..:.:|.|.:|..:.|.:|.......:|.|..|.|
plant   382 -FPEEAILSREAKDLINSLLCSVRRRLGSKGADELKAHTWFETVDWDTIFDMDAAFVPEVNDDLD 445

  Fly   408 TSNFE--DGIRHKTRREQGVAKKSLTTNMKSNDF----SGKDLPFIGYSFVHMEKSAISATTDEK 466
            |.|||  |....:|:           |:.||..:    |.||:.|:||::.:.|      ..::.
plant   446 TQNFEKFDESESETQ-----------TSSKSGPWRKMLSSKDINFVGYTYKNFE------IVNDY 493

  Fly   467 LQEKLKELLQKLKTRENEISMLKQDLLRAQQSLRKTDNKSQVVADA 512
            ....:.||.:|.|:....:..|             .||.|...:|:
plant   494 QVPGMAELKKKKKSTRPMVKSL-------------FDNGSSETSDS 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	134/391 (34%)
		S_TKc	113..383	CDD:214567	111/314 (35%)
		Smc	487..1222	CDD:224117	5/26 (19%)
		CNH	1503..1774	CDD:279162
AT2G20470	NP_001318254.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920