DRSC/TRiP Functional Genomics Resources

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Protein Alignment sti and lats2

DIOPT Version :9

Sequence 1:NP_001261768.1 Gene:sti / 39429 FlyBaseID:FBgn0002466 Length:1858 Species:Drosophila melanogaster
Sequence 2:NP_001116779.1 Gene:lats2 / 567674 ZFINID:ZDB-GENE-050119-6 Length:1140 Species:Danio rerio


Alignment Length:364 Identity:135/364 - (37%)
Similarity:196/364 - (53%) Gaps:74/364 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 RKLRVNADDFL-IKTLIGQGYFGNVHLVVERQTNDIYAMKKI-KKSVVTTSQ---VKEERDIMSI 163
            |:.:::...|: |||| |.|.||.|.|..:..|..:||||.: ||.|:..:|   ||.||||::.
Zfish   699 RRAKMDKSMFVKIKTL-GIGAFGEVCLTRKVDTGALYAMKTLRKKDVLNRNQVAHVKAERDILAE 762

  Fly   164 RNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGY 228
            .::||::.|.|:|||.||||.||:|:||||::||:.|.|.|.|.|||||:||||:|:.::|:||:
Zfish   763 ADNEWVVRLYYSFQDRDNLYFVMDYIPGGDMMSLLIRMGVFPEVLARFYVAELTLAIESVHKMGF 827

  Fly   229 VHRDIKPENILIDRFGHIKLADFG---------NAAALDRDGHV--------------------- 263
            :||||||:|||||..|||||.|||         |:....:..|:                     
Zfish   828 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGNHIRQDSMEPSDSWDDVSNCRCGD 892

  Fly   264 ----------------LSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYE 312
                            |:.|.||||:|||||:|       |.|....:     ||:||:|:|.:|
Zfish   893 RLMTLEQRATRQHQRCLAHSLVGTPNYIAPEVL-------LRKGYTQL-----CDWWSVGVILFE 945

  Fly   313 LICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYE-- 375
            ::....||......|...|::      :.:..:..|..:|:|....::|..|..:..:||...  
Zfish   946 MLVGQPPFLAPTPTEAQLKVI------NWENTLQVPPQVKLSPEAVDIIGQLCCSAEERLGGNGA 1004

  Fly   376 -RIKNHPFFSEIPWGS-IRSQVPPIIPTVRSDDDTSNFE 412
             .||.||||||:.:.| :|:|..|..|.:....|||||:
Zfish  1005 GEIKAHPFFSEVDFSSNLRTQPAPYRPKIAHPMDTSNFD 1043

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stiNP_001261768.1 PKc_like 111..452 CDD:304357 134/357 (38%)
S_TKc 113..383 CDD:214567 120/323 (37%)
Smc 487..1222 CDD:224117
CNH 1503..1774 CDD:279162
lats2NP_001116779.1 UBA_LATS2 105..145 CDD:270581
Med15 175..>635 CDD:255446
PKc_like 706..1088 CDD:304357 134/357 (38%)
S_TKc 708..1013 CDD:214567 120/323 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D759391at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.920

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