DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sti and lats1

DIOPT Version :9

Sequence 1:	NP_001261768.1	Gene:	sti / 39429	FlyBaseID:	FBgn0002466	Length:	1858	Species:	Drosophila melanogaster
Sequence 2:	NP_001018346.1	Gene:	lats1 / 553164	ZFINID:	ZDB-GENE-050523-2	Length:	1068	Species:	Danio rerio

Alignment Length:	353	Identity:	136/353 - (38%)
Similarity:	180/353 - (50%)	Gaps:	74/353 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 IKTLIGQGYFGNVHLVVERQTNDIYAMKKI-KKSVVTTSQ---VKEERDIMSIRNSEWLINLQYA 175
            |||| |.|.||.|.|..:..|..:||||.: ||.|:..:|   ||.||||::..::||::.|.|:
Zfish   648 IKTL-GIGAFGEVCLARKVDTGALYAMKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYS 711

  Fly   176 FQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILI 240
            |||.||||.||:|:||||::||:.|.|.|.||||:||:|||..|:.::|:||::||||||:||||
Zfish   712 FQDKDNLYFVMDYIPGGDMMSLLIRMGIFQEDLAQFYIAELICAVESVHKMGFIHRDIKPDNILI 776

  Fly   241 DRFGHIKLADFG-----------------------------------NAAALDR----------- 259
            ||.|||||.|||                                   |....||
Zfish   777 DRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHVRQDSMDFSMEWEDSANCRCGDRLKPLERRAARQ 841

  Fly   260 DGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSRIVSCDYWSMGIIGYELICETTPFHEDN 324
            ....|:.|.||||:|||||:|......:|            ||:||:|:|.||::....||....
Zfish   842 HQRCLAHSLVGTPNYIAPEVLLRTGYTQL------------CDWWSVGVILYEMVVGQPPFLATT 894

  Fly   325 VHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRL---SYERIKNHPFFSEI 386
            ..||..|::......|:      |...|:|....:||..|...|..||   ..:.||..|||..|
Zfish   895 PLETQMKVIRWQTSLHI------PLQAKLSPEATDLILKLCRGPDDRLGRNGADEIKAQPFFRTI 953

  Fly   387 PWG-SIRSQ-VPPIIPTVRSDDDTSNFE 412
            ... .:|.| ..|.||.:....|||||:
Zfish   954 DLSKDLRQQHQAPYIPKITHSTDTSNFD 981

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sti	NP_001261768.1	PKc_like	111..452	CDD:304357	136/353 (39%)
		S_TKc	113..383	CDD:214567	123/320 (38%)
		Smc	487..1222	CDD:224117
		CNH	1503..1774	CDD:279162
lats1	NP_001018346.1	PKc_like	644..1024	CDD:304357	136/353 (39%)
lats1	NP_001018346.1	S_TKc	645..950	CDD:214567	123/320 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010